Entity Details

Primary name Sirt2
Entity type gene
Source Source Link

Details

PrimaryID64383
RefseqGene
SymbolSirt2
Namesirtuin 2
Chromosome7
Location7
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-03-22
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsSIR2_MOUSE

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000792 heterochromatin
GO:0003682 chromatin binding
GO:0003950 NAD+ ADP-ribosyltransferase activity
GO:0004407 histone deacetylase activity
GO:0005634 nucleus
GO:0005694 chromosome
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005813 centrosome
GO:0005814 centriole
GO:0005819 spindle
GO:0005829 cytosol
GO:0005874 microtubule
GO:0005886 plasma membrane
GO:0006471 protein ADP-ribosylation
GO:0006476 protein deacetylation
GO:0006914 autophagy
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0008285 negative regulation of cell population proliferation
GO:0010507 negative regulation of autophagy
GO:0010801 negative regulation of peptidyl-threonine phosphorylation
GO:0014065 phosphatidylinositol 3-kinase signaling
GO:0016575 histone deacetylation
GO:0017136 NAD-dependent histone deacetylase activity
GO:0022011 myelination in peripheral nervous system
GO:0030426 growth cone
GO:0030496 midbody
GO:0031641 regulation of myelination
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0033010 paranodal junction
GO:0033270 paranode region of axon
GO:0033558 protein deacetylase activity
GO:0034599 cellular response to oxidative stress
GO:0034979 NAD-dependent protein deacetylase activity
GO:0034983 peptidyl-lysine deacetylation
GO:0035035 histone acetyltransferase binding
GO:0035729 cellular response to hepatocyte growth factor stimulus
GO:0035748 myelin sheath abaxonal region
GO:0042177 negative regulation of protein catabolic process
GO:0042826 histone deacetylase binding
GO:0042903 tubulin deacetylase activity
GO:0043066 negative regulation of apoptotic process
GO:0043130 ubiquitin binding
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043204 perikaryon
GO:0043209 myelin sheath
GO:0043219 lateral loop
GO:0043220 Schmidt-Lanterman incisure
GO:0043388 positive regulation of DNA binding
GO:0043491 protein kinase B signaling
GO:0044224 juxtaparanode region of axon
GO:0044242 cellular lipid catabolic process
GO:0045598 regulation of fat cell differentiation
GO:0045599 negative regulation of fat cell differentiation
GO:0045836 positive regulation of meiotic nuclear division
GO:0045843 negative regulation of striated muscle tissue development
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)
GO:0048012 hepatocyte growth factor receptor signaling pathway
GO:0048471 perinuclear region of cytoplasm
GO:0048715 negative regulation of oligodendrocyte differentiation
GO:0051301 cell division
GO:0051321 meiotic cell cycle
GO:0051726 regulation of cell cycle
GO:0051781 positive regulation of cell division
GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore
GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0061433 cellular response to caloric restriction
GO:0070403 NAD+ binding
GO:0070446 negative regulation of oligodendrocyte progenitor proliferation
GO:0070932 histone H3 deacetylation
GO:0070933 histone H4 deacetylation
GO:0071219 cellular response to molecule of bacterial origin
GO:0071456 cellular response to hypoxia
GO:0071872 cellular response to epinephrine stimulus
GO:0072686 mitotic spindle
GO:0072687 meiotic spindle
GO:0090042 tubulin deacetylation
GO:0097386 glial cell projection
GO:0097456 terminal loop
GO:0098978 glutamatergic synapse
GO:0099149 regulation of postsynaptic neurotransmitter receptor internalization
GO:1900119 positive regulation of execution phase of apoptosis
GO:1900195 positive regulation of oocyte maturation
GO:1900226 negative regulation of NLRP3 inflammasome complex assembly
GO:1900425 negative regulation of defense response to bacterium
GO:2000378 negative regulation of reactive oxygen species metabolic process
GO:2000777 positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia

Diseases

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