Entity Details

Primary name Sirt3
Entity type gene
Source Source Link

Details

PrimaryID64384
RefseqGene
SymbolSirt3
Namesirtuin 3
Chromosome7
Location7
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-03-22
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsSIR3_MOUSE

GO terms

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GOName
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005759 mitochondrial matrix
GO:0006476 protein deacetylation
GO:0008270 zinc ion binding
GO:0009060 aerobic respiration
GO:0016020 membrane
GO:0016740 transferase activity
GO:0017136 NAD-dependent histone deacetylase activity
GO:0019899 enzyme binding
GO:0032024 positive regulation of insulin secretion
GO:0032041 NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0032991 protein-containing complex
GO:0034979 NAD-dependent protein deacetylase activity
GO:0034983 peptidyl-lysine deacetylation
GO:0043565 sequence-specific DNA binding
GO:0070373 negative regulation of ERK1 and ERK2 cascade
GO:0070403 NAD+ binding
GO:0070932 histone H3 deacetylation
GO:1901671 positive regulation of superoxide dismutase activity
GO:1902553 positive regulation of catalase activity
GO:1903109 positive regulation of mitochondrial transcription
GO:2000304 positive regulation of ceramide biosynthetic process
GO:2000378 negative regulation of reactive oxygen species metabolic process
GO:2000757 negative regulation of peptidyl-lysine acetylation

Diseases

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