Entity Details

Primary name CBX4_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionO55187
EntryNameCBX4_MOUSE
FullNameE3 SUMO-protein ligase CBX4
TaxID10090
Evidenceevidence at protein level
Length551
SequenceStatuscomplete
DateCreated2001-01-24
DateModified2021-06-02

Ontological Relatives

GenesCbx4

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000976 transcription cis-regulatory region binding
GO:0003682 chromatin binding
GO:0003727 single-stranded RNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006325 chromatin organization
GO:0016604 nuclear body
GO:0016607 nuclear speck
GO:0016925 protein sumoylation
GO:0019789 SUMO transferase activity
GO:0019899 enzyme binding
GO:0031519 PcG protein complex
GO:0032183 SUMO binding
GO:0035064 methylated histone binding
GO:0035102 PRC1 complex
GO:0045892 negative regulation of transcription, DNA-templated
GO:0051219 phosphoprotein binding
GO:0061665 SUMO ligase activity

Subcellular Location

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Subcellular Location
Nucleus
Nucleus speckle

Domains

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DomainNameCategoryType
IPR000953 Chromo/chromo shadow domainDomainDomain
IPR016197 Chromo-like domain superfamilyFamilyHomologous superfamily
IPR017984 Chromo domain subgroupDomainDomain
IPR023779 Chromo domain, conserved siteSiteConserved site
IPR023780 Chromo domainDomainDomain
IPR033773 CBX family C-terminal motifSiteConserved site
IPR043531 E3 SUMO-protein ligase CBX4FamilyFamily

Diseases

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