Entity Details

Primary name Psenen
Entity type gene
Source Source Link

Details

PrimaryID66340
RefseqGene
SymbolPsenen
Namepresenilin enhancer gamma secretase subunit
Chromosome7
Location7
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-02-20
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsPEN2_MOUSE

GO terms

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GOName
GO:0005739 mitochondrion
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006509 membrane protein ectodomain proteolysis
GO:0007219 Notch signaling pathway
GO:0007220 Notch receptor processing
GO:0010950 positive regulation of endopeptidase activity
GO:0016021 integral component of membrane
GO:0016485 protein processing
GO:0019899 enzyme binding
GO:0032580 Golgi cisterna membrane
GO:0034205 amyloid-beta formation
GO:0042982 amyloid precursor protein metabolic process
GO:0042987 amyloid precursor protein catabolic process
GO:0043085 positive regulation of catalytic activity
GO:0061133 endopeptidase activator activity
GO:0070765 gamma-secretase complex
GO:0099056 integral component of presynaptic membrane

Diseases

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Interactions

5 interactions