Entity Details

Primary name Iscu
Entity type gene
Source Source Link

Details

PrimaryID66383
RefseqGene
SymbolIscu
Nameiron-sulfur cluster assembly enzyme
Chromosome5
Location5
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-02-20
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsISCU_MOUSE

GO terms

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GOName
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0005829 cytosol
GO:0006879 cellular iron ion homeostasis
GO:0008198 ferrous iron binding
GO:0016226 iron-sulfur cluster assembly
GO:0051537 2 iron, 2 sulfur cluster binding
GO:0051539 4 iron, 4 sulfur cluster binding
GO:0060090 molecular adaptor activity
GO:1902958 positive regulation of mitochondrial electron transport, NADH to ubiquinone
GO:1904234 positive regulation of aconitate hydratase activity
GO:1904439 negative regulation of iron ion import across plasma membrane

Diseases

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Interactions

6 interactions

InteractorPartnerSourcesPublicationsLink
IscuSfnBioGRID32325033 details
IscuGstm5BioGRID32325033 details
IscuHscbBioGRID32325033 details
IscuNecab2BioGRID32325033 details
IscuCfdBioGRID30550785 details
IscuFndc5BioGRID30550785 details