Entity Details

Primary name FIS1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9CQ92
EntryNameFIS1_MOUSE
FullNameMitochondrial fission 1 protein
TaxID10090
Evidenceevidence at protein level
Length152
SequenceStatuscomplete
DateCreated2003-07-19
DateModified2021-06-02

Ontological Relatives

GenesFis1

GO terms

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GOName
GO:0000266 mitochondrial fission
GO:0000422 autophagy of mitochondrion
GO:0001836 release of cytochrome c from mitochondria
GO:0005739 mitochondrion
GO:0005777 peroxisome
GO:0005778 peroxisomal membrane
GO:0005779 integral component of peroxisomal membrane
GO:0005783 endoplasmic reticulum
GO:0006626 protein targeting to mitochondrion
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0008053 mitochondrial fusion
GO:0010821 regulation of mitochondrion organization
GO:0016559 peroxisome fission
GO:0031307 integral component of mitochondrial outer membrane
GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration
GO:0032991 protein-containing complex
GO:0035584 calcium-mediated signaling using intracellular calcium source
GO:0042802 identical protein binding
GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043525 positive regulation of neuron apoptotic process
GO:0043653 mitochondrial fragmentation involved in apoptotic process
GO:0044877 protein-containing complex binding
GO:0051561 positive regulation of mitochondrial calcium ion concentration
GO:0070584 mitochondrion morphogenesis
GO:0090141 positive regulation of mitochondrial fission
GO:0090314 positive regulation of protein targeting to membrane
GO:1901653 cellular response to peptide
GO:1903579 negative regulation of ATP metabolic process
GO:1904579 cellular response to thapsigargin
GO:2000192 negative regulation of fatty acid transport
GO:2001244 positive regulation of intrinsic apoptotic signaling pathway

Subcellular Location

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Subcellular Location
Mitochondrion outer membrane
Peroxisome membrane

Domains

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DomainNameCategoryType
IPR011990 Tetratricopeptide-like helical domain superfamilyFamilyHomologous superfamily
IPR016543 Mitochondria fission 1 proteinFamilyFamily
IPR028058 Fis1, N-terminal tetratricopeptide repeatRepeatRepeat
IPR028061 Fis1, C-terminal tetratricopeptide repeatRepeatRepeat
IPR033745 Mitochondria fission protein Fis1, cytosolic domainDomainDomain

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
FIS1_MOUSEDNM1L_MOUSEBioGRID, UniProt30914652 32325033 details
FIS1_MOUSELRRK2_MOUSEBioGRID22639965 details