Entity Details

Primary name ILK_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionO55222
EntryNameILK_MOUSE
FullNameIntegrin-linked protein kinase
TaxID10090
Evidenceevidence at protein level
Length452
SequenceStatuscomplete
DateCreated2000-12-01
DateModified2021-06-02

Ontological Relatives

GenesIlk

GO terms

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GOName
GO:0000902 cell morphogenesis
GO:0001558 regulation of cell growth
GO:0001658 branching involved in ureteric bud morphogenesis
GO:0001725 stress fiber
GO:0001934 positive regulation of protein phosphorylation
GO:0001954 positive regulation of cell-matrix adhesion
GO:0003151 outflow tract morphogenesis
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005178 integrin binding
GO:0005524 ATP binding
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0005925 focal adhesion
GO:0006468 protein phosphorylation
GO:0006469 negative regulation of protein kinase activity
GO:0007160 cell-matrix adhesion
GO:0007229 integrin-mediated signaling pathway
GO:0007569 cell aging
GO:0008284 positive regulation of cell population proliferation
GO:0009967 positive regulation of signal transduction
GO:0010667 negative regulation of cardiac muscle cell apoptotic process
GO:0010761 fibroblast migration
GO:0014044 Schwann cell development
GO:0014912 negative regulation of smooth muscle cell migration
GO:0017124 SH3 domain binding
GO:0018105 peptidyl-serine phosphorylation
GO:0019901 protein kinase binding
GO:0019904 protein domain specific binding
GO:0021675 nerve development
GO:0022011 myelination in peripheral nervous system
GO:0030017 sarcomere
GO:0030027 lamellipodium
GO:0030030 cell projection organization
GO:0030335 positive regulation of cell migration
GO:0030424 axon
GO:0030513 positive regulation of BMP signaling pathway
GO:0032288 myelin assembly
GO:0032956 regulation of actin cytoskeleton organization
GO:0032991 protein-containing complex
GO:0033209 tumor necrosis factor-mediated signaling pathway
GO:0034446 substrate adhesion-dependent cell spreading
GO:0042327 positive regulation of phosphorylation
GO:0043025 neuronal cell body
GO:0043034 costamere
GO:0043066 negative regulation of apoptotic process
GO:0043195 terminal bouton
GO:0043198 dendritic shaft
GO:0043406 positive regulation of MAP kinase activity
GO:0043410 positive regulation of MAPK cascade
GO:0043491 protein kinase B signaling
GO:0043524 negative regulation of neuron apoptotic process
GO:0044877 protein-containing complex binding
GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity
GO:0045663 positive regulation of myoblast differentiation
GO:0045669 positive regulation of osteoblast differentiation
GO:0045773 positive regulation of axon extension
GO:0045893 positive regulation of transcription, DNA-templated
GO:0048662 negative regulation of smooth muscle cell proliferation
GO:0048812 neuron projection morphogenesis
GO:0050772 positive regulation of axonogenesis
GO:0050775 positive regulation of dendrite morphogenesis
GO:0051897 positive regulation of protein kinase B signaling
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:0097435 supramolecular fiber organization
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1900026 positive regulation of substrate adhesion-dependent cell spreading
GO:1901224 positive regulation of NIK/NF-kappaB signaling
GO:2000178 negative regulation of neural precursor cell proliferation

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane
Cell projection
Cytoplasm

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR001245 Serine-threonine/tyrosine-protein kinase, catalytic domainDomainDomain
IPR002110 Ankyrin repeatRepeatRepeat
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR020683 Ankyrin repeat-containing domainDomainDomain
IPR035692 Integrin-linked protein kinase, pseudokinase domainDomainDomain
IPR036770 Ankyrin repeat-containing domain superfamilyFamilyHomologous superfamily

Diseases

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