Entity Details

Primary name Derl1
Entity type gene
Source Source Link

Details

PrimaryID67819
RefseqGene
SymbolDerl1
NameDer1-like domain family, member 1
Chromosome15
Location15
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-02-20
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsDERL1_MOUSE

GO terms

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GOName
GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex
GO:0002020 protease binding
GO:0005047 signal recognition particle binding
GO:0005769 early endosome
GO:0005770 late endosome
GO:0005783 endoplasmic reticulum
GO:0006986 response to unfolded protein
GO:0016021 integral component of membrane
GO:0030176 integral component of endoplasmic reticulum membrane
GO:0030433 ubiquitin-dependent ERAD pathway
GO:0030968 endoplasmic reticulum unfolded protein response
GO:0030970 retrograde protein transport, ER to cytosol
GO:0031398 positive regulation of protein ubiquitination
GO:0031625 ubiquitin protein ligase binding
GO:0031648 protein destabilization
GO:0032092 positive regulation of protein binding
GO:0034620 cellular response to unfolded protein
GO:0036502 Derlin-1-VIMP complex
GO:0036503 ERAD pathway
GO:0036513 Derlin-1 retrotranslocation complex
GO:0042288 MHC class I protein binding
GO:0042802 identical protein binding
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0044322 endoplasmic reticulum quality control compartment
GO:0044877 protein-containing complex binding
GO:0051117 ATPase binding
GO:0051787 misfolded protein binding
GO:0071712 ER-associated misfolded protein catabolic process
GO:1990381 ubiquitin-specific protease binding

Diseases

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Interactions

5 interactions

InteractorPartnerSourcesPublicationsLink
Derl1UbcBioGRID28190767 details
Derl1Scnn1aBioGRID28137758 details
Derl1EedBioGRID24457600 details
Derl1CfdBioGRID30550785 details
Derl1Fndc5BioGRID30550785 details