Entity Details

Primary name Pink1
Entity type gene
Source Source Link

Details

PrimaryID68943
RefseqGene
SymbolPink1
NamePTEN induced putative kinase 1
Chromosome4
Location4
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-02-20
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsPINK1_MOUSE

GO terms

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GOName
GO:0000287 magnesium ion binding
GO:0000422 autophagy of mitochondrion
GO:0000785 chromatin
GO:0001934 positive regulation of protein phosphorylation
GO:0002020 protease binding
GO:0002082 regulation of oxidative phosphorylation
GO:0002931 response to ischemia
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0005743 mitochondrial inner membrane
GO:0005758 mitochondrial intermembrane space
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0006468 protein phosphorylation
GO:0006979 response to oxidative stress
GO:0007005 mitochondrion organization
GO:0010310 regulation of hydrogen peroxide metabolic process
GO:0010629 negative regulation of gene expression
GO:0010821 regulation of mitochondrion organization
GO:0010857 calcium-dependent protein kinase activity
GO:0016020 membrane
GO:0016239 positive regulation of macroautophagy
GO:0016242 negative regulation of macroautophagy
GO:0016301 kinase activity
GO:0016567 protein ubiquitination
GO:0018105 peptidyl-serine phosphorylation
GO:0022904 respiratory electron transport chain
GO:0030424 axon
GO:0030426 growth cone
GO:0031307 integral component of mitochondrial outer membrane
GO:0031396 regulation of protein ubiquitination
GO:0031625 ubiquitin protein ligase binding
GO:0032226 positive regulation of synaptic transmission, dopaminergic
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0033603 positive regulation of dopamine secretion
GO:0033605 positive regulation of catecholamine secretion
GO:0034599 cellular response to oxidative stress
GO:0035307 positive regulation of protein dephosphorylation
GO:0035556 intracellular signal transduction
GO:0036289 peptidyl-serine autophosphorylation
GO:0042981 regulation of apoptotic process
GO:0043066 negative regulation of apoptotic process
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043254 regulation of protein-containing complex assembly
GO:0043422 protein kinase B binding
GO:0043523 regulation of neuron apoptotic process
GO:0043524 negative regulation of neuron apoptotic process
GO:0044297 cell body
GO:0044877 protein-containing complex binding
GO:0045727 positive regulation of translation
GO:0048471 perinuclear region of cytoplasm
GO:0050821 protein stabilization
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0051881 regulation of mitochondrial membrane potential
GO:0055131 C3HC4-type RING finger domain binding
GO:0071456 cellular response to hypoxia
GO:0072655 establishment of protein localization to mitochondrion
GO:0072656 maintenance of protein location in mitochondrion
GO:0090141 positive regulation of mitochondrial fission
GO:0090200 positive regulation of release of cytochrome c from mitochondria
GO:0090258 negative regulation of mitochondrial fission
GO:0097237 cellular response to toxic substance
GO:0097449 astrocyte projection
GO:0098779 positive regulation of mitophagy in response to mitochondrial depolarization
GO:0099074 mitochondrion to lysosome transport
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1900407 regulation of cellular response to oxidative stress
GO:1901215 negative regulation of neuron death
GO:1901727 positive regulation of histone deacetylase activity
GO:1902902 negative regulation of autophagosome assembly
GO:1902958 positive regulation of mitochondrial electron transport, NADH to ubiquinone
GO:1903147 negative regulation of autophagy of mitochondrion
GO:1903202 negative regulation of oxidative stress-induced cell death
GO:1903214 regulation of protein targeting to mitochondrion
GO:1903298 negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway
GO:1903384 negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway
GO:1903751 negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide
GO:1903852 positive regulation of cristae formation
GO:1904783 positive regulation of NMDA glutamate receptor activity
GO:1904841 TORC2 complex binding
GO:1904881 cellular response to hydrogen sulfide
GO:1904925 positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization
GO:2000377 regulation of reactive oxygen species metabolic process
GO:2000378 negative regulation of reactive oxygen species metabolic process
GO:2001243 negative regulation of intrinsic apoptotic signaling pathway

Diseases

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Interactions

7 interactions