Entity Details

Primary name MED12_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionA2AGH6
EntryNameMED12_MOUSE
FullNameMediator of RNA polymerase II transcription subunit 12
TaxID10090
Evidenceevidence at protein level
Length2190
SequenceStatuscomplete
DateCreated2008-01-15
DateModified2021-06-02

Ontological Relatives

GenesMed12

GO terms

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GOName
GO:0000151 ubiquitin ligase complex
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001756 somitogenesis
GO:0001843 neural tube closure
GO:0003682 chromatin binding
GO:0003712 transcription coregulator activity
GO:0003713 transcription coactivator activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007492 endoderm development
GO:0007507 heart development
GO:0008013 beta-catenin binding
GO:0008022 protein C-terminus binding
GO:0008134 transcription factor binding
GO:0014003 oligodendrocyte development
GO:0014044 Schwann cell development
GO:0016567 protein ubiquitination
GO:0016592 mediator complex
GO:0019827 stem cell population maintenance
GO:0019904 protein domain specific binding
GO:0021510 spinal cord development
GO:0021915 neural tube development
GO:0036342 post-anal tail morphogenesis
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046966 thyroid hormone receptor binding
GO:0048568 embryonic organ development
GO:0048702 embryonic neurocranium morphogenesis
GO:0060070 canonical Wnt signaling pathway
GO:0060071 Wnt signaling pathway, planar cell polarity pathway
GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter
GO:0061630 ubiquitin protein ligase activity
GO:0090245 axis elongation involved in somitogenesis
GO:1990403 embryonic brain development

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR019035 Mediator complex, subunit Med12DomainDomain
IPR021989 Mediator complex, subunit Med12, catenin-bindingDomainDomain
IPR021990 Mediator complex, subunit Med12, LCEWAV-domainDomainDomain

Diseases

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