Entity Details

Primary name Hdac8
Entity type gene
Source Source Link

Details

PrimaryID70315
RefseqGene
SymbolHdac8
Namehistone deacetylase 8
ChromosomeX
LocationX
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-02-20
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsHDAC8_MOUSE

GO terms

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GOName
GO:0000118 histone deacetylase complex
GO:0003682 chromatin binding
GO:0004407 histone deacetylase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0006325 chromatin organization
GO:0007062 sister chromatid cohesion
GO:0008134 transcription factor binding
GO:0010629 negative regulation of gene expression
GO:0019213 deacetylase activity
GO:0030544 Hsp70 protein binding
GO:0031397 negative regulation of protein ubiquitination
GO:0031647 regulation of protein stability
GO:0032041 NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0032204 regulation of telomere maintenance
GO:0035984 cellular response to trichostatin A
GO:0045668 negative regulation of osteoblast differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046872 metal ion binding
GO:0051879 Hsp90 protein binding
GO:0070932 histone H3 deacetylation
GO:0070933 histone H4 deacetylation
GO:0071922 regulation of cohesin loading
GO:1903496 response to 11-deoxycorticosterone
GO:1904322 cellular response to forskolin
GO:2000616 negative regulation of histone H3-K9 acetylation

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
Hdac8EsrraBioGRID20484414 details
Hdac8Xpo7IntAct29748336 unassigned1673 details
Hdac8CDC73MINT29774127 details