Entity Details

Primary name Mutyh
Entity type gene
Source Source Link

Details

PrimaryID70603
RefseqGene
SymbolMutyh
NamemutY DNA glycosylase
Chromosome4
Location4
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-02-20
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsMUTYH_MOUSE

GO terms

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GOName
GO:0000701 purine-specific mismatch base pair DNA N-glycosylase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005739 mitochondrion
GO:0006281 DNA repair
GO:0006284 base-excision repair
GO:0006298 mismatch repair
GO:0006979 response to oxidative stress
GO:0019104 DNA N-glycosylase activity
GO:0032357 oxidized purine DNA binding
GO:0032407 MutSalpha complex binding
GO:0034039 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity
GO:0035485 adenine/guanine mispair binding
GO:0046872 metal ion binding
GO:0051539 4 iron, 4 sulfur cluster binding
GO:0060546 negative regulation of necroptotic process

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
MutyhHUS1BioGRID26021743 details
MutyhRAD9ABioGRID26021743 details
MutyhApex1BioGRID24209961 details