Entity Details

Primary name NCF2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionO70145
EntryNameNCF2_MOUSE
FullNameNeutrophil cytosol factor 2
TaxID10090
Evidenceevidence at protein level
Length525
SequenceStatuscomplete
DateCreated2007-12-04
DateModified2021-06-02

Ontological Relatives

GenesNcf2

GO terms

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GOName
GO:0001669 acrosomal vesicle
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006742 NADP catabolic process
GO:0006801 superoxide metabolic process
GO:0006909 phagocytosis
GO:0008022 protein C-terminus binding
GO:0009749 response to glucose
GO:0014070 response to organic cyclic compound
GO:0016020 membrane
GO:0016175 superoxide-generating NAD(P)H oxidase activity
GO:0016176 superoxide-generating NADPH oxidase activator activity
GO:0031267 small GTPase binding
GO:0032496 response to lipopolysaccharide
GO:0032870 cellular response to hormone stimulus
GO:0042554 superoxide anion generation
GO:0043020 NADPH oxidase complex
GO:0043525 positive regulation of neuron apoptotic process
GO:0045730 respiratory burst
GO:0045777 positive regulation of blood pressure

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000270 PB1 domainDomainDomain
IPR001440 Tetratricopeptide repeat 1RepeatRepeat
IPR001452 SH3 domainDomainDomain
IPR011990 Tetratricopeptide-like helical domain superfamilyFamilyHomologous superfamily
IPR019734 Tetratricopeptide repeatRepeatRepeat
IPR034885 Neutrophil cytosol factor 2, PB1 domainDomainDomain
IPR034889 Neutrophil cytosol factor 2FamilyFamily
IPR035546 Neutrophil cytosol factor 2, SH3 domain 1DomainDomain
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
NCF2_MOUSEPRDX6_MOUSEBioGRID, IntAct23401562 details
NCF2_MOUSEPRDX6_HUMANIntAct23401562 details