Entity Details

Primary name Sirt4
Entity type gene
Source Source Link

Details

PrimaryID75387
RefseqGene
SymbolSirt4
Namesirtuin 4
Chromosome5
Location5
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-02-20
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsSIR4_MOUSE

GO terms

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GOName
GO:0000820 regulation of glutamine family amino acid metabolic process
GO:0003950 NAD+ ADP-ribosyltransferase activity
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005759 mitochondrial matrix
GO:0006471 protein ADP-ribosylation
GO:0006541 glutamine metabolic process
GO:0006974 cellular response to DNA damage stimulus
GO:0008270 zinc ion binding
GO:0010667 negative regulation of cardiac muscle cell apoptotic process
GO:0034979 NAD-dependent protein deacetylase activity
GO:0034983 peptidyl-lysine deacetylation
GO:0046322 negative regulation of fatty acid oxidation
GO:0046676 negative regulation of insulin secretion
GO:0046889 positive regulation of lipid biosynthetic process
GO:0047708 biotinidase activity
GO:0061690 lipoamidase activity
GO:0070403 NAD+ binding
GO:0071456 cellular response to hypoxia
GO:0072350 tricarboxylic acid metabolic process
GO:1903217 negative regulation of protein processing involved in protein targeting to mitochondrion
GO:1904182 regulation of pyruvate dehydrogenase activity

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
Sirt4Glud1BioGRID16959573 details
Sirt4Sirt3BioGRID32325033 details
Sirt4Slc25a5BioGRID32325033 details