Entity Details

Primary name Smurf1
Entity type gene
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Details

PrimaryID75788
RefseqGene
SymbolSmurf1
NameSMAD specific E3 ubiquitin protein ligase 1
Chromosome5
Location5
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-02-20
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsSMUF1_MOUSE

GO terms

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GOName
GO:0000209 protein polyubiquitination
GO:0004842 ubiquitin-protein transferase activity
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0006611 protein export from nucleus
GO:0016567 protein ubiquitination
GO:0030154 cell differentiation
GO:0030279 negative regulation of ossification
GO:0030424 axon
GO:0030509 BMP signaling pathway
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030514 negative regulation of BMP signaling pathway
GO:0030579 ubiquitin-dependent SMAD protein catabolic process
GO:0032801 receptor catabolic process
GO:0034394 protein localization to cell surface
GO:0043025 neuronal cell body
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045732 positive regulation of protein catabolic process
GO:0061630 ubiquitin protein ligase activity
GO:0061734 parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
GO:0061736 engulfment of target by autophagosome
GO:0061753 substrate localization to autophagosome
GO:0070411 I-SMAD binding
GO:0070412 R-SMAD binding
GO:0071211 protein targeting to vacuole involved in autophagy
GO:1903861 positive regulation of dendrite extension
GO:2000060 positive regulation of ubiquitin-dependent protein catabolic process

Diseases

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