Entity Details

Primary name Dock2
Entity type gene
Source Source Link

Details

PrimaryID94176
RefseqGene
SymbolDock2
Namededicator of cyto-kinesis 2
Chromosome11
Location11
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-08-02
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsDOCK2_MOUSE

GO terms

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GOName
GO:0001766 membrane raft polarization
GO:0001768 establishment of T cell polarity
GO:0001771 immunological synapse formation
GO:0002277 myeloid dendritic cell activation involved in immune response
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005096 GTPase activator activity
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0006935 chemotaxis
GO:0007010 cytoskeleton organization
GO:0007264 small GTPase mediated signal transduction
GO:0012505 endomembrane system
GO:0016020 membrane
GO:0030036 actin cytoskeleton organization
GO:0035022 positive regulation of Rac protein signal transduction
GO:0042098 T cell proliferation
GO:0042110 T cell activation
GO:0042608 T cell receptor binding
GO:0044351 macropinocytosis
GO:0045059 positive thymic T cell selection
GO:0045060 negative thymic T cell selection
GO:0046631 alpha-beta T cell activation
GO:0046633 alpha-beta T cell proliferation
GO:0050766 positive regulation of phagocytosis

Diseases

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Interactions

7 interactions