Entity Details

Primary name Kdm1a
Entity type gene
Source Source Link

Details

PrimaryID99982
RefseqGene
SymbolKdm1a
Namelysine (K)-specific demethylase 1A
Chromosome4
Location4 68.8 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-08-16
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsKDM1A_MOUSE

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000781 chromosome, telomeric region
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0002039 p53 binding
GO:0002052 positive regulation of neuroblast proliferation
GO:0003682 chromatin binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006342 chromatin silencing
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006482 protein demethylation
GO:0008134 transcription factor binding
GO:0010569 regulation of double-strand break repair via homologous recombination
GO:0010725 regulation of primitive erythrocyte differentiation
GO:0010976 positive regulation of neuron projection development
GO:0016491 oxidoreductase activity
GO:0019899 enzyme binding
GO:0021983 pituitary gland development
GO:0030154 cell differentiation
GO:0030374 nuclear receptor coactivator activity
GO:0030851 granulocyte differentiation
GO:0032091 negative regulation of protein binding
GO:0032451 demethylase activity
GO:0032452 histone demethylase activity
GO:0032453 histone demethylase activity (H3-K4 specific)
GO:0032454 histone demethylase activity (H3-K9 specific)
GO:0032991 protein-containing complex
GO:0033169 histone H3-K9 demethylation
GO:0033184 positive regulation of histone ubiquitination
GO:0034644 cellular response to UV
GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)
GO:0034649 histone demethylase activity (H3-monomethyl-K4 specific)
GO:0034720 histone H3-K4 demethylation
GO:0035563 positive regulation of chromatin binding
GO:0043426 MRF binding
GO:0043433 negative regulation of DNA-binding transcription factor activity
GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator
GO:0045648 positive regulation of erythrocyte differentiation
GO:0045654 positive regulation of megakaryocyte differentiation
GO:0045793 positive regulation of cell size
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046098 guanine metabolic process
GO:0050660 flavin adenine dinucleotide binding
GO:0050681 androgen receptor binding
GO:0050767 regulation of neurogenesis
GO:0050768 negative regulation of neurogenesis
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0051572 negative regulation of histone H3-K4 methylation
GO:0051573 negative regulation of histone H3-K9 methylation
GO:0055001 muscle cell development
GO:0061752 telomeric repeat-containing RNA binding
GO:0071480 cellular response to gamma radiation
GO:0120162 positive regulation of cold-induced thermogenesis
GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:1903827 regulation of cellular protein localization
GO:1990138 neuron projection extension
GO:1990391 DNA repair complex
GO:1990841 promoter-specific chromatin binding
GO:2000179 positive regulation of neural precursor cell proliferation
GO:2000648 positive regulation of stem cell proliferation

Diseases

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Interactions

76 interactions

InteractorPartnerSourcesPublicationsLink
Kdm1aGfi1bBioGRID, UniProt17707228 details
Kdm1aArBioGRID16079795 17277772 details
Kdm1aKdm4cBioGRID17277772 details
Kdm1aOTUD4BioGRID31138677 details
Kdm1aRnf2BioGRID, IntAct17296600 22496869 26206133 details
Kdm1aNanogBioGRID, MINT18454139 23892456 details
Kdm1aRBPJLDIP17392792 details
Kdm1aRcor1BioGRID, DIP17392792 22297846 26206133 details
Kdm1aLcorDIP17392792 details
Kdm1aPou1f1DIP17392792 details
Kdm1aZeb1DIP17392792 details
Kdm1aHdac2BioGRID, DIP20404188 22297846 26206133 details
Kdm1aHdac1BioGRID, DIP20404188 22297846 26206133 26974661 details
Kdm1aCebpaDIP26974661 details
Kdm1aZfpm1BioGRID, IntAct19654328 details
Kdm1aMef2dBioGRID20833138 details
Kdm1aMyod1BioGRID20833138 details
Kdm1aFoxp3BioGRID22922362 details
Kdm1aChaf1aBioGRID26365490 details
Kdm1aEsrrbBioGRID26206133 details
Kdm1aRcor2BioGRID26206133 27112428 details
Kdm1aRbpjBioGRID27112428 details
Kdm1aHes1BioGRID27112428 details
Kdm1aKdm2bBioGRID, IntAct17296600 details
Kdm1aPou5f1BioGRID, IntAct20362541 20362542 22083510 details
Kdm1aTfcp2l1BioGRID, IntAct20362541 details
Kdm1aCtbp1BioGRID, DIP17392792 26206133 details
Kdm1aTal1BioGRID, DIP19497860 details
Kdm1aChd4BioGRID, DIP22297846 26206133 details
Kdm1aTnikBioGRID, IntAct28671696 details
Kdm1aTsc1BioGRID, IntAct28671696 details
Kdm1aXpo7IntAct29748336 unassigned1673 details
Kdm1aEedBioGRID24457600 details
Kdm1aElf5BioGRID26584622 details
Kdm1aGse1BioGRID26206133 details
Kdm1aRreb1BioGRID26206133 details
Kdm1aZfp516BioGRID26206133 details
Kdm1aZmym2BioGRID26206133 details
Kdm1aRcor3BioGRID26206133 details
Kdm1aSupt5BioGRID26206133 details
Kdm1aTrim14BioGRID26206133 details
Kdm1aXpo5BioGRID26206133 details
Kdm1aAdnpBioGRID26206133 details
Kdm1aCtbp2BioGRID26206133 details
Kdm1aPolr2aBioGRID26206133 details
Kdm1aKdm5aBioGRID26206133 details
Kdm1aCopeBioGRID26206133 details
Kdm1aSepsecsBioGRID26206133 details
Kdm1aSupt16BioGRID26206133 details
Kdm1aHmg20bBioGRID26206133 details
Kdm1aHmg20aBioGRID26206133 details
Kdm1aDhx15BioGRID26206133 details
Kdm1aMsh6BioGRID26206133 details
Kdm1aPhf21aBioGRID26206133 details
Kdm1aMcm2BioGRID26206133 details
Kdm1aHmgb2BioGRID26206133 details
Kdm1aMta3BioGRID26206133 details
Kdm1aUsp7BioGRID26206133 details
Kdm1aPhc2BioGRID26206133 details
Kdm1aRpa1BioGRID26206133 details
Kdm1aLta4hBioGRID26206133 details
Kdm1aPspc1BioGRID26206133 details
Kdm1aFpgsBioGRID26206133 details
Kdm1aTfap2cBioGRID26206133 details
Kdm1aDnaja1BioGRID26206133 details
Kdm1aEml2BioGRID26206133 details
Kdm1aPolr2bBioGRID26206133 details
Kdm1aSugt1BioGRID26206133 details
Kdm1aIkBioGRID26206133 details
Kdm1aAp2m1BioGRID26206133 details
Kdm1aCdc23BioGRID26206133 details
Kdm1aEdc3BioGRID26206133 details
Kdm1aDdx1BioGRID26206133 details
Kdm1aAtg16l1BioGRID30196744 details
Kdm1aAtxn1BioGRID30457570 details
Kdm1aUnkBioGRID25737280 details