Entity Details

Primary name HDAC6
Entity type gene
Source Source Link

Details

PrimaryID10013
RefseqGeneNG_012560
SymbolHDAC6
Namehistone deacetylase 6
ChromosomeX
LocationXp11.23
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-11-28
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsHDAC6_HUMAN

GO terms

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GOName
GO:0000118 histone deacetylase complex
GO:0000209 protein polyubiquitination
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0003779 actin binding
GO:0004407 histone deacetylase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005771 multivesicular body
GO:0005829 cytosol
GO:0005874 microtubule
GO:0005875 microtubule associated complex
GO:0005901 caveola
GO:0006476 protein deacetylation
GO:0006515 protein quality control for misfolded or incompletely synthesized proteins
GO:0006886 intracellular protein transport
GO:0007026 negative regulation of microtubule depolymerization
GO:0008013 beta-catenin binding
GO:0008017 microtubule binding
GO:0008270 zinc ion binding
GO:0010506 regulation of autophagy
GO:0010634 positive regulation of epithelial cell migration
GO:0010727 negative regulation of hydrogen peroxide metabolic process
GO:0016234 inclusion body
GO:0016235 aggresome
GO:0016241 regulation of macroautophagy
GO:0016575 histone deacetylation
GO:0019899 enzyme binding
GO:0030424 axon
GO:0030425 dendrite
GO:0031252 cell leading edge
GO:0031333 negative regulation of protein-containing complex assembly
GO:0031593 polyubiquitin modification-dependent protein binding
GO:0031625 ubiquitin protein ligase binding
GO:0031647 regulation of protein stability
GO:0031648 protein destabilization
GO:0032041 NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0032418 lysosome localization
GO:0032984 protein-containing complex disassembly
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0033558 protein deacetylase activity
GO:0034983 peptidyl-lysine deacetylation
GO:0035967 cellular response to topologically incorrect protein
GO:0035973 aggrephagy
GO:0040029 regulation of gene expression, epigenetic
GO:0042826 histone deacetylase binding
GO:0042903 tubulin deacetylase activity
GO:0043014 alpha-tubulin binding
GO:0043130 ubiquitin binding
GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO:0043204 perikaryon
GO:0043242 negative regulation of protein-containing complex disassembly
GO:0045598 regulation of fat cell differentiation
GO:0045861 negative regulation of proteolysis
GO:0045892 negative regulation of transcription, DNA-templated
GO:0048156 tau protein binding
GO:0048471 perinuclear region of cytoplasm
GO:0048487 beta-tubulin binding
GO:0048668 collateral sprouting
GO:0051354 negative regulation of oxidoreductase activity
GO:0051646 mitochondrion localization
GO:0051787 misfolded protein binding
GO:0051788 response to misfolded protein
GO:0051879 Hsp90 protein binding
GO:0060271 cilium assembly
GO:0060632 regulation of microtubule-based movement
GO:0060765 regulation of androgen receptor signaling pathway
GO:0060997 dendritic spine morphogenesis
GO:0061734 parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
GO:0070201 regulation of establishment of protein localization
GO:0070301 cellular response to hydrogen peroxide
GO:0070840 dynein complex binding
GO:0070842 aggresome assembly
GO:0070845 polyubiquitinated misfolded protein transport
GO:0070846 Hsp90 deacetylation
GO:0070848 response to growth factor
GO:0071218 cellular response to misfolded protein
GO:0090042 tubulin deacetylation
GO:1901300 positive regulation of hydrogen peroxide-mediated programmed cell death
GO:1903146 regulation of autophagy of mitochondrion
GO:2000273 positive regulation of signaling receptor activity

Diseases

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Interactions

7 interactions