Entity Details

Primary name PARP2
Entity type gene
Source Source Link

Details

PrimaryID10038
RefseqGeneNG_033959
SymbolPARP2
Namepoly(ADP-ribose) polymerase 2
Chromosome14
Location14q11.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-05-08
ModificationDate2021-06-13

Ontological Relatives

UniProt IDsPARP2_HUMAN

GO terms

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GOName
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003950 NAD+ ADP-ribosyltransferase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0006281 DNA repair
GO:0006284 base-excision repair
GO:0006302 double-strand break repair
GO:0006471 protein ADP-ribosylation
GO:0016570 histone modification
GO:0018312 peptidyl-serine ADP-ribosylation
GO:0030592 DNA ADP-ribosylation
GO:0031491 nucleosome binding
GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development
GO:0070212 protein poly-ADP-ribosylation
GO:0070213 protein auto-ADP-ribosylation
GO:0090734 site of DNA damage
GO:0097191 extrinsic apoptotic signaling pathway
GO:0140294 NAD DNA ADP-ribosyltransferase activity
GO:1901215 negative regulation of neuron death
GO:1990404 protein ADP-ribosylase activity

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
PARP2Npm1BioGRID15615785 details
PARP2Psmb5BioGRID, IntAct26496610 details