Entity Details

Primary name NR1H3
Entity type gene
Source Source Link

Details

PrimaryID10062
RefseqGeneNG_030392
SymbolNR1H3
Namenuclear receptor subfamily 1 group H member 3
Chromosome11
Location11p11.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-09-21
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsNR1H3_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0008270 zinc ion binding
GO:0010745 negative regulation of macrophage derived foam cell differentiation
GO:0010867 positive regulation of triglyceride biosynthetic process
GO:0010875 positive regulation of cholesterol efflux
GO:0010887 negative regulation of cholesterol storage
GO:0015485 cholesterol binding
GO:0030154 cell differentiation
GO:0030522 intracellular receptor signaling pathway
GO:0032270 positive regulation of cellular protein metabolic process
GO:0032369 negative regulation of lipid transport
GO:0032376 positive regulation of cholesterol transport
GO:0032570 response to progesterone
GO:0032810 sterol response element binding
GO:0034145 positive regulation of toll-like receptor 4 signaling pathway
GO:0036151 phosphatidylcholine acyl-chain remodeling
GO:0042632 cholesterol homeostasis
GO:0042752 regulation of circadian rhythm
GO:0043031 negative regulation of macrophage activation
GO:0043235 receptor complex
GO:0043277 apoptotic cell clearance
GO:0045723 positive regulation of fatty acid biosynthetic process
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048550 negative regulation of pinocytosis
GO:0050728 negative regulation of inflammatory response
GO:0051006 positive regulation of lipoprotein lipase activity
GO:0055088 lipid homeostasis
GO:0055092 sterol homeostasis
GO:0060336 negative regulation of interferon-gamma-mediated signaling pathway
GO:0070328 triglyceride homeostasis
GO:0071222 cellular response to lipopolysaccharide
GO:0090188 negative regulation of pancreatic juice secretion
GO:0090341 negative regulation of secretion of lysosomal enzymes
GO:0090575 RNA polymerase II transcription regulator complex
GO:0120163 negative regulation of cold-induced thermogenesis
GO:1903573 negative regulation of response to endoplasmic reticulum stress

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
NR1H3PparaBioGRID8621574 details
NR1H3Hacd3IntAct25036637 details
NR1H3Men1MINT25962847 details