Entity Details

Primary name HUWE1
Entity type gene
Source Source Link

Details

PrimaryID10075
RefseqGeneNG_016261
SymbolHUWE1
NameHECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
ChromosomeX
LocationXp11.22
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-05-22
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsHUWE1_HUMAN

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0000209 protein polyubiquitination
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0004842 ubiquitin-protein transferase activity
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006284 base-excision repair
GO:0006513 protein monoubiquitination
GO:0007030 Golgi organization
GO:0010637 negative regulation of mitochondrial fusion
GO:0016020 membrane
GO:0016567 protein ubiquitination
GO:0016574 histone ubiquitination
GO:0030154 cell differentiation
GO:0031398 positive regulation of protein ubiquitination
GO:0032922 circadian regulation of gene expression
GO:0034774 secretory granule lumen
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043312 neutrophil degranulation
GO:0045732 positive regulation of protein catabolic process
GO:0061025 membrane fusion
GO:0061630 ubiquitin protein ligase activity
GO:0070062 extracellular exosome
GO:0098779 positive regulation of mitophagy in response to mitochondrial depolarization
GO:1903955 positive regulation of protein targeting to mitochondrion
GO:1904813 ficolin-1-rich granule lumen

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
HUWE1Cep78BioGRID, IntAct26496610 details
HUWE1Vcpip1BioGRID, IntAct26496610 details
HUWE1Rnf183BioGRID31732153 details