Entity Details

Primary name CDK5
Entity type gene
Source Source Link

Details

PrimaryID1020
RefseqGeneNG_042167
SymbolCDK5
Namecyclin dependent kinase 5
Chromosome7
Location7q36.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-12-30
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsCDK5_HUMAN

GO terms

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GOName
GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle
GO:0000226 microtubule cytoskeleton organization
GO:0001764 neuron migration
GO:0001963 synaptic transmission, dopaminergic
GO:0002039 p53 binding
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004693 cyclin-dependent protein serine/threonine kinase activity
GO:0005176 ErbB-2 class receptor binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005874 microtubule
GO:0005886 plasma membrane
GO:0006468 protein phosphorylation
GO:0006886 intracellular protein transport
GO:0006913 nucleocytoplasmic transport
GO:0007005 mitochondrion organization
GO:0007160 cell-matrix adhesion
GO:0007268 chemical synaptic transmission
GO:0007409 axonogenesis
GO:0007416 synapse assembly
GO:0007519 skeletal muscle tissue development
GO:0008045 motor neuron axon guidance
GO:0008542 visual learning
GO:0009611 response to wounding
GO:0014044 Schwann cell development
GO:0014069 postsynaptic density
GO:0016020 membrane
GO:0016079 synaptic vesicle exocytosis
GO:0016241 regulation of macroautophagy
GO:0016301 kinase activity
GO:0016310 phosphorylation
GO:0016533 protein kinase 5 complex
GO:0016572 histone phosphorylation
GO:0018105 peptidyl-serine phosphorylation
GO:0018107 peptidyl-threonine phosphorylation
GO:0019233 sensory perception of pain
GO:0019901 protein kinase binding
GO:0021697 cerebellar cortex formation
GO:0021766 hippocampus development
GO:0021819 layer formation in cerebral cortex
GO:0021954 central nervous system neuron development
GO:0022038 corpus callosum development
GO:0030027 lamellipodium
GO:0030054 cell junction
GO:0030175 filopodium
GO:0030182 neuron differentiation
GO:0030334 regulation of cell migration
GO:0030424 axon
GO:0030425 dendrite
GO:0030426 growth cone
GO:0030517 negative regulation of axon extension
GO:0030549 acetylcholine receptor activator activity
GO:0030866 cortical actin cytoskeleton organization
GO:0031175 neuron projection development
GO:0031397 negative regulation of protein ubiquitination
GO:0031594 neuromuscular junction
GO:0031914 negative regulation of synaptic plasticity
GO:0032092 positive regulation of protein binding
GO:0032801 receptor catabolic process
GO:0034352 positive regulation of glial cell apoptotic process
GO:0035249 synaptic transmission, glutamatergic
GO:0035418 protein localization to synapse
GO:0042501 serine phosphorylation of STAT protein
GO:0042981 regulation of apoptotic process
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0043113 receptor clustering
GO:0043125 ErbB-3 class receptor binding
GO:0043204 perikaryon
GO:0043525 positive regulation of neuron apoptotic process
GO:0045786 negative regulation of cell cycle
GO:0045860 positive regulation of protein kinase activity
GO:0045861 negative regulation of proteolysis
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045956 positive regulation of calcium ion-dependent exocytosis
GO:0046777 protein autophosphorylation
GO:0046826 negative regulation of protein export from nucleus
GO:0046875 ephrin receptor binding
GO:0048148 behavioral response to cocaine
GO:0048156 tau protein binding
GO:0048167 regulation of synaptic plasticity
GO:0048488 synaptic vesicle endocytosis
GO:0048489 synaptic vesicle transport
GO:0048511 rhythmic process
GO:0048675 axon extension
GO:0048709 oligodendrocyte differentiation
GO:0048813 dendrite morphogenesis
GO:0050321 tau-protein kinase activity
GO:0051301 cell division
GO:0051402 neuron apoptotic process
GO:0051879 Hsp90 protein binding
GO:0051966 regulation of synaptic transmission, glutamatergic
GO:0060079 excitatory postsynaptic potential
GO:0061001 regulation of dendritic spine morphogenesis
GO:0070509 calcium ion import
GO:0090314 positive regulation of protein targeting to membrane
GO:0098685 Schaffer collateral - CA1 synapse
GO:0098793 presynapse
GO:0098883 synapse pruning
GO:0098978 glutamatergic synapse
GO:0099635 voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1901215 negative regulation of neuron death
GO:1901387 positive regulation of voltage-gated calcium channel activity
GO:1901796 regulation of signal transduction by p53 class mediator
GO:1903076 regulation of protein localization to plasma membrane
GO:1903421 regulation of synaptic vesicle recycling
GO:1904646 cellular response to amyloid-beta
GO:2000251 positive regulation of actin cytoskeleton reorganization

Diseases

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Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
CDK5MaptMINT17078951 details
CDK5Suds3BioGRID15489224 details
CDK5Cdk1BioGRID, IntAct20360068 details
CDK5Dppa3BioGRID28712289 details