Entity Details

Primary name CDKN1B
Entity type gene
Source Source Link

Details

PrimaryID1027
RefseqGeneNG_016341
SymbolCDKN1B
Namecyclin dependent kinase inhibitor 1B
Chromosome12
Location12p13.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-05
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsCDN1B_HUMAN

GO terms

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GOName
GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0000082 G1/S transition of mitotic cell cycle
GO:0004860 protein kinase inhibitor activity
GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0005829 cytosol
GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0007507 heart development
GO:0008285 negative regulation of cell population proliferation
GO:0010942 positive regulation of cell death
GO:0019221 cytokine-mediated signaling pathway
GO:0019901 protein kinase binding
GO:0019903 protein phosphatase binding
GO:0030308 negative regulation of cell growth
GO:0030332 cyclin binding
GO:0031464 Cul4A-RING E3 ubiquitin ligase complex
GO:0033673 negative regulation of kinase activity
GO:0042326 negative regulation of phosphorylation
GO:0043231 intracellular membrane-bounded organelle
GO:0044877 protein-containing complex binding
GO:0045732 positive regulation of protein catabolic process
GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0045786 negative regulation of cell cycle
GO:0045787 positive regulation of cell cycle
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045930 negative regulation of mitotic cell cycle
GO:0048102 autophagic cell death
GO:0051087 chaperone binding
GO:0071285 cellular response to lithium ion
GO:1902806 regulation of cell cycle G1/S phase transition
GO:1904030 negative regulation of cyclin-dependent protein kinase activity
GO:1904706 negative regulation of vascular associated smooth muscle cell proliferation
GO:1905179 negative regulation of cardiac muscle tissue regeneration

Diseases

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Interactions

8 interactions