Entity Details

Primary name ABCA7
Entity type gene
Source Source Link

Details

PrimaryID10347
RefseqGeneNG_046909
SymbolABCA7
NameATP binding cassette subfamily A member 7
Chromosome19
Location19p13.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-06-11
ModificationDate2021-06-13

Ontological Relatives

UniProt IDsABCA7_HUMAN

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0001891 phagocytic cup
GO:0005319 lipid transporter activity
GO:0005524 ATP binding
GO:0005548 phospholipid transporter activity
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0006869 lipid transport
GO:0006909 phagocytosis
GO:0007613 memory
GO:0008542 visual learning
GO:0009986 cell surface
GO:0010875 positive regulation of cholesterol efflux
GO:0016021 integral component of membrane
GO:0018149 peptide cross-linking
GO:0019216 regulation of lipid metabolic process
GO:0030054 cell junction
GO:0031901 early endosome membrane
GO:0032587 ruffle membrane
GO:0033344 cholesterol efflux
GO:0033700 phospholipid efflux
GO:0034188 apolipoprotein A-I receptor activity
GO:0034205 amyloid-beta formation
GO:0034380 high-density lipoprotein particle assembly
GO:0034504 protein localization to nucleus
GO:0038027 apolipoprotein A-I-mediated signaling pathway
GO:0042626 ATPase-coupled transmembrane transporter activity
GO:0042985 negative regulation of amyloid precursor protein biosynthetic process
GO:0043231 intracellular membrane-bounded organelle
GO:0043409 negative regulation of MAPK cascade
GO:0044857 plasma membrane raft organization
GO:0045332 phospholipid translocation
GO:0045806 negative regulation of endocytosis
GO:0050766 positive regulation of phagocytosis
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0090554 phosphatidylcholine floppase activity
GO:0090556 phosphatidylserine floppase activity
GO:0097386 glial cell projection
GO:0140328 floppase activity
GO:0150094 amyloid-beta clearance by cellular catabolic process
GO:1900223 positive regulation of amyloid-beta clearance
GO:1901076 positive regulation of engulfment of apoptotic cell
GO:1902430 negative regulation of amyloid-beta formation
GO:1902991 regulation of amyloid precursor protein catabolic process
GO:1902995 positive regulation of phospholipid efflux
GO:1903898 negative regulation of PERK-mediated unfolded protein response
GO:2000010 positive regulation of protein localization to cell surface

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
ABCA7Haus1BioGRID, IntAct26496610 details