Entity Details

Primary name PRPF8
Entity type gene
Source Source Link

Details

PrimaryID10594
RefseqGeneNG_009118
SymbolPRPF8
Namepre-mRNA processing factor 8
Chromosome17
Location17p13.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-07-02
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsPRP8_HUMAN

GO terms

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GOName
GO:0000244 spliceosomal tri-snRNP complex assembly
GO:0000375 RNA splicing, via transesterification reactions
GO:0000398 mRNA splicing, via spliceosome
GO:0003723 RNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005682 U5 snRNP
GO:0006397 mRNA processing
GO:0008380 RNA splicing
GO:0016020 membrane
GO:0016607 nuclear speck
GO:0017070 U6 snRNA binding
GO:0030619 U1 snRNA binding
GO:0030620 U2 snRNA binding
GO:0030623 U5 snRNA binding
GO:0046540 U4/U6 x U5 tri-snRNP complex
GO:0070122 isopeptidase activity
GO:0070530 K63-linked polyubiquitin modification-dependent protein binding
GO:0071005 U2-type precatalytic spliceosome
GO:0071006 U2-type catalytic step 1 spliceosome
GO:0071007 U2-type catalytic step 2 spliceosome
GO:0071013 catalytic step 2 spliceosome
GO:0071222 cellular response to lipopolysaccharide
GO:0071356 cellular response to tumor necrosis factor
GO:0097157 pre-mRNA intronic binding

Diseases

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Interactions

14 interactions

InteractorPartnerSourcesPublicationsLink
PRPF8Cdk1BioGRID, IntAct20360068 details
PRPF8Prpf8BioGRID, IntAct20360068 details
PRPF8Snw1BioGRID, IntAct20360068 26496610 details
PRPF8Cdc5lBioGRID, IntAct20360068 details
PRPF8Smad6MINT23455153 details
PRPF8Bcas2BioGRID, IntAct26496610 details
PRPF8Pqbp1BioGRID, IntAct26496610 details
PRPF8Ccdc12BioGRID, IntAct26496610 details
PRPF8JupBioGRID, IntAct26496610 details
PRPF8Wbp11BioGRID, IntAct26496610 details
PRPF8Sart1BioGRID, IntAct26496610 details
PRPF8Prdm16MINT30462309 details
PRPF8MecomMINT30462309 details
PRPF8Dnajc17BioGRID29773831 details