Entity Details

Primary name CFL1
Entity type gene
Source Source Link

Details

PrimaryID1072
RefseqGene
SymbolCFL1
Namecofilin 1
Chromosome11
Location11q13.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1995-07-11
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsCOF1_HUMAN

GO terms

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GOName
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005925 focal adhesion
GO:0007010 cytoskeleton organization
GO:0007266 Rho protein signal transduction
GO:0009615 response to virus
GO:0015629 actin cytoskeleton
GO:0016020 membrane
GO:0016032 viral process
GO:0016363 nuclear matrix
GO:0022604 regulation of cell morphogenesis
GO:0030027 lamellipodium
GO:0030036 actin cytoskeleton organization
GO:0030042 actin filament depolymerization
GO:0030043 actin filament fragmentation
GO:0031258 lamellipodium membrane
GO:0031982 vesicle
GO:0032587 ruffle membrane
GO:0035722 interleukin-12-mediated signaling pathway
GO:0040019 positive regulation of embryonic development
GO:0043066 negative regulation of apoptotic process
GO:0044794 positive regulation by host of viral process
GO:0048870 cell motility
GO:0051014 actin filament severing
GO:0051015 actin filament binding
GO:0051293 establishment of spindle localization
GO:0061001 regulation of dendritic spine morphogenesis
GO:0070062 extracellular exosome

Diseases

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Interactions

12 interactions

InteractorPartnerSourcesPublicationsLink
CFL1Dnm1lMINT31063459 details
CFL1Lima1BioGRID, IntAct26496610 details
CFL1Calml3BioGRID, IntAct26496610 details
CFL1Tmod3BioGRID, IntAct26496610 details
CFL1Tpm1BioGRID, IntAct26496610 details
CFL1Coro1cBioGRID, IntAct26496610 details
CFL1Myh9BioGRID, IntAct26496610 details
CFL1Myo1cBioGRID, IntAct26496610 details
CFL1Sestd1BioGRID, IntAct26496610 details
CFL1Myh10BioGRID, IntAct26496610 details
CFL1Prdm16MINT30462309 details
CFL1MecomMINT30462309 details