Entity Details

Primary name PLK2
Entity type gene
Source Source Link

Details

PrimaryID10769
RefseqGene
SymbolPLK2
Namepolo like kinase 2
Chromosome5
Location5q11.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-07-19
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsPLK2_HUMAN

GO terms

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GOName
GO:0000082 G1/S transition of mitotic cell cycle
GO:0000278 mitotic cell cycle
GO:0000785 chromatin
GO:0000922 spindle pole
GO:0002862 negative regulation of inflammatory response to antigenic stimulus
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005814 centriole
GO:0005829 cytosol
GO:0006468 protein phosphorylation
GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0007052 mitotic spindle organization
GO:0007093 mitotic cell cycle checkpoint signaling
GO:0007265 Ras protein signal transduction
GO:0007613 memory
GO:0010508 positive regulation of autophagy
GO:0016525 negative regulation of angiogenesis
GO:0018105 peptidyl-serine phosphorylation
GO:0030425 dendrite
GO:0032092 positive regulation of protein binding
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032465 regulation of cytokinesis
GO:0032486 Rap protein signal transduction
GO:0043008 ATP-dependent protein binding
GO:0043066 negative regulation of apoptotic process
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0044877 protein-containing complex binding
GO:0045732 positive regulation of protein catabolic process
GO:0046599 regulation of centriole replication
GO:0048167 regulation of synaptic plasticity
GO:0060291 long-term synaptic potentiation
GO:0060292 long-term synaptic depression
GO:0061000 negative regulation of dendritic spine development
GO:0071866 negative regulation of apoptotic process in bone marrow cell
GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:2000773 negative regulation of cellular senescence

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
PLK2Plk2BioGRID, IntAct20360068 details
PLK2Xpo1IntAct26673895 details