Entity Details

Primary name FRS2
Entity type gene
Source Source Link

Details

PrimaryID10818
RefseqGene
SymbolFRS2
Namefibroblast growth factor receptor substrate 2
Chromosome12
Location12q15
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-07-23
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsFRS2_HUMAN

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0000186 obsolete activation of MAPKK activity
GO:0000187 obsolete activation of MAPK activity
GO:0001702 gastrulation with mouth forming second
GO:0001759 organ induction
GO:0003281 ventricular septum development
GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity
GO:0005104 fibroblast growth factor receptor binding
GO:0005168 neurotrophin TRKA receptor binding
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005912 adherens junction
GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007405 neuroblast proliferation
GO:0007411 axon guidance
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0008595 anterior/posterior axis specification, embryo
GO:0012505 endomembrane system
GO:0016020 membrane
GO:0019211 phosphatase activator activity
GO:0030900 forebrain development
GO:0042981 regulation of apoptotic process
GO:0046619 lens placode formation involved in camera-type eye formation
GO:0048011 neurotrophin TRK receptor signaling pathway
GO:0050678 regulation of epithelial cell proliferation
GO:0051897 positive regulation of protein kinase B signaling
GO:0060527 prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis
GO:0070307 lens fiber cell development
GO:0070372 regulation of ERK1 and ERK2 cascade
GO:2000726 negative regulation of cardiac muscle cell differentiation

Diseases

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Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
FRS2Ptpn11BioGRID25159185 details
FRS2Grb2BioGRID25159185 details
FRS2Gab1BioGRID25159185 details
FRS2Coro1cBioGRID, IntAct26496610 details