Entity Details

Primary name WWP2
Entity type gene
Source Source Link

Details

PrimaryID11060
RefseqGene
SymbolWWP2
NameWW domain containing E3 ubiquitin protein ligase 2
Chromosome16
Location16q22.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-08-21
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsWWP2_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000151 ubiquitin ligase complex
GO:0000209 protein polyubiquitination
GO:0004842 ubiquitin-protein transferase activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006464 cellular protein modification process
GO:0006858 extracellular transport
GO:0008134 transcription factor binding
GO:0010629 negative regulation of gene expression
GO:0016020 membrane
GO:0016567 protein ubiquitination
GO:0032410 negative regulation of transporter activity
GO:0034765 regulation of ion transmembrane transport
GO:0042391 regulation of membrane potential
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043433 negative regulation of DNA-binding transcription factor activity
GO:0045732 positive regulation of protein catabolic process
GO:0045746 negative regulation of Notch signaling pathway
GO:0045892 negative regulation of transcription, DNA-templated
GO:0046718 viral entry into host cell
GO:0051224 negative regulation of protein transport
GO:0051865 protein autoubiquitination
GO:0061630 ubiquitin protein ligase activity
GO:0070062 extracellular exosome
GO:0070534 protein K63-linked ubiquitination
GO:1901016 regulation of potassium ion transmembrane transporter activity

Diseases

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Interactions

6 interactions

InteractorPartnerSourcesPublicationsLink
WWP2Ndfip1BioGRID11748237 details
WWP2Wbp1lBioGRID31845480 details
WWP2Bmpr1aBioGRID, IntAct26496610 details
WWP2Eea1BioGRID, IntAct26496610 details
WWP2Csnk1dBioGRID, IntAct26496610 details
WWP2Sod1BioGRID, IntAct26496610 details