Entity Details

Primary name GLYM_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9CZN7
EntryNameGLYM_MOUSE
FullNameSerine hydroxymethyltransferase, mitochondrial
TaxID10090
Evidenceevidence at protein level
Length504
SequenceStatuscomplete
DateCreated2018-03-28
DateModified2021-06-02

Ontological Relatives

GenesShmt2

GO terms

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GOName
GO:0000900 translation repressor activity, mRNA regulatory element binding
GO:0002082 regulation of oxidative phosphorylation
GO:0003682 chromatin binding
GO:0004372 glycine hydroxymethyltransferase activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005758 mitochondrial intermembrane space
GO:0005759 mitochondrial matrix
GO:0005829 cytosol
GO:0006544 glycine metabolic process
GO:0006545 glycine biosynthetic process
GO:0006563 L-serine metabolic process
GO:0006564 L-serine biosynthetic process
GO:0006565 L-serine catabolic process
GO:0006730 one-carbon metabolic process
GO:0008270 zinc ion binding
GO:0008284 positive regulation of cell population proliferation
GO:0008732 L-allo-threonine aldolase activity
GO:0009113 purine nucleobase biosynthetic process
GO:0015630 microtubule cytoskeleton
GO:0016597 amino acid binding
GO:0019264 glycine biosynthetic process from serine
GO:0030170 pyridoxal phosphate binding
GO:0034340 response to type I interferon
GO:0035999 tetrahydrofolate interconversion
GO:0042645 mitochondrial nucleoid
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0046653 tetrahydrofolate metabolic process
GO:0046655 folic acid metabolic process
GO:0048027 mRNA 5'-UTR binding
GO:0050897 cobalt ion binding
GO:0051262 protein tetramerization
GO:0051289 protein homotetramerization
GO:0070129 regulation of mitochondrial translation
GO:0070536 protein K63-linked deubiquitination
GO:0070552 BRISC complex
GO:0070905 serine binding
GO:1903715 regulation of aerobic respiration

Subcellular Location

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Subcellular Location
Cytoplasm
Mitochondrion
Mitochondrion inner membrane
Mitochondrion matrix
Nucleus

Domains

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DomainNameCategoryType
IPR001085 Serine hydroxymethyltransferaseFamilyFamily
IPR015421 Pyridoxal phosphate-dependent transferase, major domainFamilyHomologous superfamily
IPR015422 Pyridoxal phosphate-dependent transferase, small domainFamilyHomologous superfamily
IPR015424 Pyridoxal phosphate-dependent transferaseFamilyHomologous superfamily
IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding siteSiteBinding site
IPR039429 Serine hydroxymethyltransferase-like domainDomainDomain

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
GLYM_MOUSESET_MOUSEBioGRID17309103 details