Entity Details

Primary name TOPBP1
Entity type gene
Source Source Link

Details

PrimaryID11073
RefseqGene
SymbolTOPBP1
NameDNA topoisomerase II binding protein 1
Chromosome3
Location3q22.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-09-15
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsTOPB1_HUMAN

GO terms

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GOName
GO:0000794 condensed nuclear chromosome
GO:0000922 spindle pole
GO:0001673 male germ cell nucleus
GO:0003677 DNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0005737 cytoplasm
GO:0005815 microtubule organizing center
GO:0005886 plasma membrane
GO:0006259 DNA metabolic process
GO:0006260 DNA replication
GO:0006270 DNA replication initiation
GO:0006281 DNA repair
GO:0006974 cellular response to DNA damage stimulus
GO:0007095 mitotic G2 DNA damage checkpoint signaling
GO:0008022 protein C-terminus binding
GO:0010212 response to ionizing radiation
GO:0015629 actin cytoskeleton
GO:0016604 nuclear body
GO:0016605 PML body
GO:0033314 mitotic DNA replication checkpoint signaling
GO:0042802 identical protein binding
GO:0043231 intracellular membrane-bounded organelle
GO:1901796 regulation of signal transduction by p53 class mediator

Diseases

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Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
TOPBP1PpargBioGRID27197753 details
TOPBP1Hus1BioGRID25911100 details
TOPBP1Plk1BioGRID, IntAct20360068 details
TOPBP1Rrbp1BioGRID, IntAct26496610 details