Entity Details

Primary name AMRA1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionA2AH22
EntryNameAMRA1_MOUSE
FullNameActivating molecule in BECN1-regulated autophagy protein 1
TaxID10090
Evidenceevidence at protein level
Length1300
SequenceStatuscomplete
DateCreated2008-01-15
DateModified2021-06-02

Ontological Relatives

GenesAmbra1

GO terms

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GOName
GO:0000045 autophagosome assembly
GO:0000422 autophagy of mitochondrion
GO:0000423 mitophagy
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005776 autophagosome
GO:0005829 cytosol
GO:0005930 axoneme
GO:0006914 autophagy
GO:0008285 negative regulation of cell population proliferation
GO:0009267 cellular response to starvation
GO:0010508 positive regulation of autophagy
GO:0010667 negative regulation of cardiac muscle cell apoptotic process
GO:0021915 neural tube development
GO:0030154 cell differentiation
GO:0031625 ubiquitin protein ligase binding
GO:0043231 intracellular membrane-bounded organelle
GO:0043524 negative regulation of neuron apoptotic process
GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity
GO:0045335 phagocytic vesicle
GO:0051020 GTPase binding
GO:0098780 response to mitochondrial depolarisation

Subcellular Location

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Subcellular Location
Cytoplasmic vesicle

Domains

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DomainNameCategoryType
IPR001680 WD40 repeatRepeatRepeat
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR019775 WD40 repeat, conserved siteSiteConserved site
IPR036322 WD40-repeat-containing domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

3 interactions