Entity Details

Primary name PHB2
Entity type gene
Source Source Link

Details

PrimaryID11331
RefseqGene
SymbolPHB2
Nameprohibitin 2
Chromosome12
Location12p13.31
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-09-18
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsPHB2_HUMAN

GO terms

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GOName
GO:0000423 mitophagy
GO:0002639 positive regulation of immunoglobulin production
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0005743 mitochondrial inner membrane
GO:0005886 plasma membrane
GO:0006606 protein import into nucleus
GO:0006851 mitochondrial calcium ion transmembrane transport
GO:0007005 mitochondrion organization
GO:0007062 sister chromatid cohesion
GO:0007202 activation of phospholipase C activity
GO:0008022 protein C-terminus binding
GO:0009611 response to wounding
GO:0009986 cell surface
GO:0014069 postsynaptic density
GO:0016363 nuclear matrix
GO:0016477 cell migration
GO:0023035 CD40 signaling pathway
GO:0030331 estrogen receptor binding
GO:0030424 axon
GO:0031536 positive regulation of exit from mitosis
GO:0032991 protein-containing complex
GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway
GO:0033218 amide binding
GO:0033600 negative regulation of mammary gland epithelial cell proliferation
GO:0035632 mitochondrial prohibitin complex
GO:0039520 induction by virus of host autophagy
GO:0039529 RIG-I signaling pathway
GO:0042113 B cell activation
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043066 negative regulation of apoptotic process
GO:0043433 negative regulation of DNA-binding transcription factor activity
GO:0045892 negative regulation of transcription, DNA-templated
GO:0046625 sphingolipid binding
GO:0046982 protein heterodimerization activity
GO:0047485 protein N-terminus binding
GO:0048786 presynaptic active zone
GO:0050821 protein stabilization
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0060744 mammary gland branching involved in thelarche
GO:0060749 mammary gland alveolus development
GO:0060762 regulation of branching involved in mammary gland duct morphogenesis
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0071300 cellular response to retinoic acid
GO:0071456 cellular response to hypoxia
GO:0071944 cell periphery
GO:0098978 glutamatergic synapse
GO:0098982 GABA-ergic synapse
GO:0140374 antiviral innate immune response
GO:1900208 regulation of cardiolipin metabolic process
GO:1901224 positive regulation of NIK/NF-kappaB signaling
GO:1902808 positive regulation of cell cycle G1/S phase transition
GO:1904959 regulation of cytochrome-c oxidase activity
GO:1990051 activation of protein kinase C activity

Diseases

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Interactions

26 interactions

InteractorPartnerSourcesPublicationsLink
PHB2Hdac1BioGRID15140878 details
PHB2Rc3h1IntAct23663784 details
PHB2Rc3h2IntAct23663784 details
PHB2Rab5cBioGRID, IntAct26496610 details
PHB2Rmdn3BioGRID, IntAct26496610 details
PHB2Kctd5BioGRID, IntAct26496610 details
PHB2Myh10BioGRID, IntAct26496610 details
PHB2Rab11aBioGRID, IntAct26496610 details
PHB2Eef1a1BioGRID, IntAct26496610 details
PHB2Chmp4bBioGRID, IntAct26496610 details
PHB2Lima1BioGRID, IntAct26496610 details
PHB2Tmem109BioGRID, IntAct26496610 details
PHB2Atp2a2BioGRID, IntAct26496610 details
PHB2Calml3BioGRID, IntAct26496610 details
PHB2Aifm1BioGRID, IntAct26496610 details
PHB2Mtx2BioGRID, IntAct26496610 details
PHB2Ufl1BioGRID, IntAct26496610 details
PHB2Tmed2BioGRID, IntAct26496610 details
PHB2VimBioGRID, IntAct26496610 details
PHB2JmyUniProt25015719 details
PHB2Prdm16MINT30462309 details
PHB2MecomMINT30462309 details
PHB2Dnajc11MINT31550165 details
PHB2Kif23BioGRID20360068 details
PHB2AI837181BioGRID20360068 details
PHB2Rnf183BioGRID31732153 details