Entity Details

Primary name NLRP3
Entity type gene
Source Source Link

Details

PrimaryID114548
RefseqGeneNG_007509
SymbolNLRP3
NameNLR family pyrin domain containing 3
Chromosome1
Location1q44
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-09-10
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsNLRP3_HUMAN

GO terms

Show/Hide Table
GOName
GO:0000139 Golgi membrane
GO:0002523 leukocyte migration involved in inflammatory response
GO:0002674 negative regulation of acute inflammatory response
GO:0002830 positive regulation of type 2 immune response
GO:0005524 ATP binding
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
GO:0006915 apoptotic process
GO:0006952 defense response
GO:0006954 inflammatory response
GO:0007165 signal transduction
GO:0008134 transcription factor binding
GO:0009595 detection of biotic stimulus
GO:0014070 response to organic cyclic compound
GO:0016579 protein deubiquitination
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0032691 negative regulation of interleukin-1 beta production
GO:0032731 positive regulation of interleukin-1 beta production
GO:0032753 positive regulation of interleukin-4 production
GO:0035590 purinergic nucleotide receptor signaling pathway
GO:0042802 identical protein binding
GO:0042834 peptidoglycan binding
GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043565 sequence-specific DNA binding
GO:0045087 innate immune response
GO:0045471 response to ethanol
GO:0045630 positive regulation of T-helper 2 cell differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0050728 negative regulation of inflammatory response
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0071222 cellular response to lipopolysaccharide
GO:0072559 NLRP3 inflammasome complex
GO:1901223 negative regulation of NIK/NF-kappaB signaling
GO:2000553 positive regulation of T-helper 2 cell cytokine production

Diseases

Show/Hide Table

Interactions

7 interactions