Entity Details

Primary name GRK4_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionO70291
EntryNameGRK4_MOUSE
FullNameG protein-coupled receptor kinase 4
TaxID10090
Evidenceevidence at transcript level
Length574
SequenceStatuscomplete
DateCreated2004-05-24
DateModified2021-06-02

Ontological Relatives

GenesGrk4

GO terms

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GOName
GO:0002029 desensitization of G protein-coupled receptor signaling pathway
GO:0002031 G protein-coupled receptor internalization
GO:0004703 G protein-coupled receptor kinase activity
GO:0005524 ATP binding
GO:0005829 cytosol
GO:0005938 cell cortex
GO:0006468 protein phosphorylation
GO:0007165 signal transduction
GO:0030425 dendrite
GO:0031623 receptor internalization
GO:0043025 neuronal cell body
GO:0050254 rhodopsin kinase activity

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000239 GPCR kinaseFamilyFamily
IPR000719 Protein kinase domainDomainDomain
IPR000961 AGC-kinase, C-terminalDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR016137 RGS domainDomainDomain
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR036305 RGS domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink