Entity Details

Primary name TWST2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9D030
EntryNameTWST2_MOUSE
FullNameTwist-related protein 2
TaxID10090
Evidenceevidence at protein level
Length160
SequenceStatuscomplete
DateCreated2003-07-11
DateModified2021-06-02

Ontological Relatives

GenesTwist2

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001649 osteoblast differentiation
GO:0003682 chromatin binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0008134 transcription factor binding
GO:0008285 negative regulation of cell population proliferation
GO:0010838 positive regulation of keratinocyte proliferation
GO:0019904 protein domain specific binding
GO:0030335 positive regulation of cell migration
GO:0032502 developmental process
GO:0032720 negative regulation of tumor necrosis factor production
GO:0043066 negative regulation of apoptotic process
GO:0043392 negative regulation of DNA binding
GO:0044092 negative regulation of molecular function
GO:0045638 negative regulation of myeloid cell differentiation
GO:0045668 negative regulation of osteoblast differentiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0046983 protein dimerization activity
GO:0048701 embryonic cranial skeleton morphogenesis
GO:0060325 face morphogenesis
GO:0061303 cornea development in camera-type eye

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR011598 Myc-type, basic helix-loop-helix (bHLH) domainDomainDomain
IPR015789 Twist-relatedFamilyFamily
IPR036638 Helix-loop-helix DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
TWST2_MOUSETFE2_HUMANBioGRID9050988 details
TWST2_MOUSERUNX2_MOUSEIntAct20655471 details