Entity Details

Primary name GRK6_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionO70293
EntryNameGRK6_MOUSE
FullNameG protein-coupled receptor kinase 6
TaxID10090
Evidenceevidence at protein level
Length576
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesGrk6

GO terms

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GOName
GO:0002029 desensitization of G protein-coupled receptor signaling pathway
GO:0004672 protein kinase activity
GO:0004703 G protein-coupled receptor kinase activity
GO:0005524 ATP binding
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006468 protein phosphorylation
GO:0010360 negative regulation of anion channel activity
GO:0016055 Wnt signaling pathway
GO:0047696 beta-adrenergic receptor kinase activity

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR000239 GPCR kinaseFamilyFamily
IPR000719 Protein kinase domainDomainDomain
IPR000961 AGC-kinase, C-terminalDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR016137 RGS domainDomainDomain
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR036305 RGS domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
GRK6_MOUSEOPSD_MOUSEMINT10446210 details