Entity Details

Primary name CPS1
Entity type gene
Source Source Link

Details

PrimaryID1373
RefseqGeneNG_008285
SymbolCPS1
Namecarbamoyl-phosphate synthase 1
Chromosome2
Location2q34
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1989-11-29
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsCPSM_HUMAN

GO terms

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GOName
GO:0000050 urea cycle
GO:0004087 carbamoyl-phosphate synthase (ammonia) activity
GO:0004088 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GO:0004175 endopeptidase activity
GO:0005509 calcium ion binding
GO:0005524 ATP binding
GO:0005543 phospholipid binding
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005743 mitochondrial inner membrane
GO:0005759 mitochondrial matrix
GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process
GO:0006541 glutamine metabolic process
GO:0006807 nitrogen compound metabolic process
GO:0007494 midgut development
GO:0009636 response to toxic substance
GO:0010043 response to zinc ion
GO:0014075 response to amine
GO:0016595 glutamate binding
GO:0019240 citrulline biosynthetic process
GO:0019433 triglyceride catabolic process
GO:0032094 response to food
GO:0032496 response to lipopolysaccharide
GO:0032991 protein-containing complex
GO:0042311 vasodilation
GO:0042493 response to drug
GO:0042594 response to starvation
GO:0042645 mitochondrial nucleoid
GO:0043200 response to amino acid
GO:0044344 cellular response to fibroblast growth factor stimulus
GO:0044877 protein-containing complex binding
GO:0046209 nitric oxide metabolic process
GO:0050667 homocysteine metabolic process
GO:0055081 anion homeostasis
GO:0060416 response to growth hormone
GO:0070365 hepatocyte differentiation
GO:0070409 carbamoyl phosphate biosynthetic process
GO:0071242 cellular response to ammonium ion
GO:0071320 cellular response to cAMP
GO:0071377 cellular response to glucagon stimulus
GO:0071400 cellular response to oleic acid
GO:0071548 response to dexamethasone
GO:0072341 modified amino acid binding

Diseases

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Interactions

11 interactions

InteractorPartnerSourcesPublicationsLink
CPS1Sirt5IntAct19410549 details
CPS1Cdk1BioGRID, IntAct20360068 details
CPS1Csnk1eBioGRID, IntAct20360068 details
CPS1Tubg1BioGRID, IntAct26496610 details
CPS1Mad2l1BioGRID, IntAct26496610 details
CPS1Rpl35BioGRID, IntAct26496610 details
CPS1Ruvbl1BioGRID, IntAct26496610 details
CPS1Bag2BioGRID, IntAct26496610 details
CPS1Ormdl2IntAct26496610 details
CPS1Lgals3bpBioGRID, IntAct26496610 details
CPS1Ormdl1BioGRID26496610 details