Entity Details

Primary name CSK
Entity type gene
Source Source Link

Details

PrimaryID1445
RefseqGene
SymbolCSK
NameC-terminal Src kinase
Chromosome15
Location15q24.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1993-10-21
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsCSK_HUMAN

GO terms

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GOName
GO:0002250 adaptive immune response
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0006468 protein phosphorylation
GO:0007420 brain development
GO:0008022 protein C-terminus binding
GO:0008285 negative regulation of cell population proliferation
GO:0010989 negative regulation of low-density lipoprotein particle clearance
GO:0019221 cytokine-mediated signaling pathway
GO:0019903 protein phosphatase binding
GO:0031295 T cell costimulation
GO:0032715 negative regulation of interleukin-6 production
GO:0033673 negative regulation of kinase activity
GO:0034236 protein kinase A catalytic subunit binding
GO:0034332 adherens junction organization
GO:0042802 identical protein binding
GO:0042997 negative regulation of Golgi to plasma membrane protein transport
GO:0043406 positive regulation of MAP kinase activity
GO:0045121 membrane raft
GO:0045779 negative regulation of bone resorption
GO:0046777 protein autophosphorylation
GO:0046872 metal ion binding
GO:0048709 oligodendrocyte differentiation
GO:0050765 negative regulation of phagocytosis
GO:0050852 T cell receptor signaling pathway
GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway
GO:0070062 extracellular exosome
GO:0070064 proline-rich region binding
GO:0070373 negative regulation of ERK1 and ERK2 cascade
GO:0071375 cellular response to peptide hormone stimulus

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
CSKDok3MINT14993273 details
CSKCskBioGRID, IntAct20360068 details
CSKSlamf7UniProt19151721 details