Entity Details

Primary name KAT8_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9D1P2
EntryNameKAT8_MOUSE
FullNameHistone acetyltransferase KAT8
TaxID10090
Evidenceevidence at protein level
Length458
SequenceStatuscomplete
DateCreated2005-07-05
DateModified2021-06-02

Ontological Relatives

GenesKat8

GO terms

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GOName
GO:0000123 histone acetyltransferase complex
GO:0000776 kinetochore
GO:0003712 transcription coregulator activity
GO:0004402 histone acetyltransferase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0008134 transcription factor binding
GO:0010506 regulation of autophagy
GO:0016363 nuclear matrix
GO:0016407 acetyltransferase activity
GO:0016573 histone acetylation
GO:0019899 enzyme binding
GO:0030099 myeloid cell differentiation
GO:0035064 methylated histone binding
GO:0042393 histone binding
GO:0043981 histone H4-K5 acetylation
GO:0043982 histone H4-K8 acetylation
GO:0043984 histone H4-K16 acetylation
GO:0043995 histone acetyltransferase activity (H4-K5 specific)
GO:0043996 histone acetyltransferase activity (H4-K8 specific)
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046872 metal ion binding
GO:0046972 histone acetyltransferase activity (H4-K16 specific)
GO:0071339 MLL1 complex
GO:0072487 MSL complex

Subcellular Location

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Subcellular Location
Chromosome
Nucleus

Domains

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DomainNameCategoryType
IPR000953 Chromo/chromo shadow domainDomainDomain
IPR002717 Histone acetyltransferase domain, MYST-typeDomainDomain
IPR016181 Acyl-CoA N-acyltransferaseFamilyHomologous superfamily
IPR016197 Chromo-like domain superfamilyFamilyHomologous superfamily
IPR025995 RNA binding activity-knot of a chromodomainDomainDomain
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR037906 Histone acetyltransferase KAT8FamilyFamily
IPR040706 MYST, zinc finger domainDomainDomain

Diseases

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