Entity Details

Primary name CTSZ
Entity type gene
Source Source Link

Details

PrimaryID1522
RefseqGeneNG_023300
SymbolCTSZ
Namecathepsin Z
Chromosome20
Location20q13.32
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-27
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsCATZ_HUMAN

GO terms

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GOName
GO:0002003 angiotensin maturation
GO:0004180 carboxypeptidase activity
GO:0004197 cysteine-type endopeptidase activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005764 lysosome
GO:0005783 endoplasmic reticulum
GO:0005788 endoplasmic reticulum lumen
GO:0005886 plasma membrane
GO:0006508 proteolysis
GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport
GO:0008234 cysteine-type peptidase activity
GO:0010757 negative regulation of plasminogen activation
GO:0030134 COPII-coated ER to Golgi transport vesicle
GO:0031410 cytoplasmic vesicle
GO:0032091 negative regulation of protein binding
GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane
GO:0035580 specific granule lumen
GO:0043312 neutrophil degranulation
GO:0048208 COPII vesicle coating
GO:0051603 proteolysis involved in cellular protein catabolic process
GO:0062023 collagen-containing extracellular matrix
GO:0070062 extracellular exosome
GO:0099738 cell cortex region
GO:1901214 regulation of neuron death
GO:1904813 ficolin-1-rich granule lumen

Diseases

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Interactions

6 interactions

InteractorPartnerSourcesPublicationsLink
CTSZMsnBioGRID, IntAct26496610 details
CTSZSgo2aBioGRID, IntAct26496610 details
CTSZCep55BioGRID, IntAct26496610 details
CTSZSpred2BioGRID, IntAct26496610 details
CTSZKifc1BioGRID26496610 details
CTSZLyplal1BioGRID26496610 details