Entity Details

Primary name GRK2
Entity type gene
Source Source Link

Details

PrimaryID156
RefseqGene
SymbolGRK2
NameG protein-coupled receptor kinase 2
Chromosome11
Location11q13.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-07-27
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsARBK1_HUMAN

GO terms

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GOName
GO:0002029 desensitization of G protein-coupled receptor signaling pathway
GO:0003108 negative regulation of the force of heart contraction by chemical signal
GO:0004672 protein kinase activity
GO:0004703 G protein-coupled receptor kinase activity
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005929 cilium
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007213 G protein-coupled acetylcholine receptor signaling pathway
GO:0007217 tachykinin receptor signaling pathway
GO:0007507 heart development
GO:0016020 membrane
GO:0018105 peptidyl-serine phosphorylation
GO:0018107 peptidyl-threonine phosphorylation
GO:0019079 viral genome replication
GO:0031623 receptor internalization
GO:0031694 alpha-2A adrenergic receptor binding
GO:0031755 Edg-2 lysophosphatidic acid receptor binding
GO:0033605 positive regulation of catecholamine secretion
GO:0045202 synapse
GO:0045988 negative regulation of striated muscle contraction
GO:0046718 viral entry into host cell
GO:0047696 beta-adrenergic receptor kinase activity
GO:0060048 cardiac muscle contraction
GO:1901081 negative regulation of relaxation of smooth muscle

Diseases

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Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
GRK2Rapgef3BioGRID20861385 details
GRK2Opn4IntAct22159583 details
GRK2Tnpo1BioGRID, IntAct26496610 details
GRK2Rfx5BioGRID, IntAct26496610 details