Entity Details

Primary name AP2A1
Entity type gene
Source Source Link

Details

PrimaryID160
RefseqGene
SymbolAP2A1
Nameadaptor related protein complex 2 subunit alpha 1
Chromosome19
Location19q13.33
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-08-21
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsAP2A1_HUMAN

GO terms

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GOName
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006886 intracellular protein transport
GO:0006895 Golgi to endosome transport
GO:0006897 endocytosis
GO:0006898 receptor-mediated endocytosis
GO:0008022 protein C-terminus binding
GO:0010976 positive regulation of neuron projection development
GO:0016020 membrane
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0019901 protein kinase binding
GO:0030122 AP-2 adaptor complex
GO:0030130 clathrin coat of trans-Golgi network vesicle
GO:0030666 endocytic vesicle membrane
GO:0030669 clathrin-coated endocytic vesicle membrane
GO:0032433 filopodium tip
GO:0032802 low-density lipoprotein particle receptor catabolic process
GO:0034383 low-density lipoprotein particle clearance
GO:0035615 clathrin adaptor activity
GO:0036020 endolysosome membrane
GO:0044877 protein-containing complex binding
GO:0045334 clathrin-coated endocytic vesicle
GO:0048013 ephrin receptor signaling pathway
GO:0048260 positive regulation of receptor-mediated endocytosis
GO:0050690 regulation of defense response to virus by virus
GO:0050750 low-density lipoprotein particle receptor binding
GO:0060071 Wnt signaling pathway, planar cell polarity pathway
GO:0061024 membrane organization
GO:0072583 clathrin-dependent endocytosis
GO:0140312 cargo adaptor activity
GO:1900126 negative regulation of hyaluronan biosynthetic process

Diseases

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Interactions

20 interactions

InteractorPartnerSourcesPublicationsLink
AP2A1Eps15BioGRID12057195 details
AP2A1Csnk1eBioGRID, IntAct20360068 details
AP2A1Edc4BioGRID, IntAct20360068 details
AP2A1Dab2UniProt22323290 details
AP2A1Ppp6r3IntAct24255178 details
AP2A1NumbBioGRID, IntAct23211419 details
AP2A1Ppp1cbBioGRID, IntAct26496610 details
AP2A1Cd2apBioGRID, IntAct26496610 details
AP2A1Myh10BioGRID, IntAct26496610 details
AP2A1ActbBioGRID, IntAct26496610 details
AP2A1FlnbBioGRID, IntAct26496610 details
AP2A1Lima1BioGRID, IntAct26496610 details
AP2A1Calml3BioGRID, IntAct26496610 details
AP2A1Tpm1BioGRID, IntAct26496610 details
AP2A1Coro1cBioGRID, IntAct26496610 details
AP2A1Myh9BioGRID, IntAct26496610 details
AP2A1Myo1cBioGRID, IntAct26496610 details
AP2A1Mcm3BioGRID, IntAct26496610 details
AP2A1Uso1BioGRID, IntAct26496610 details
AP2A1Xpo1IntAct26673895 details