Entity Details

Primary name DAB2
Entity type gene
Source Source Link

Details

PrimaryID1601
RefseqGeneNG_030312
SymbolDAB2
NameDAB adaptor protein 2
Chromosome5
Location5p13.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-07-29
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsDAB2_HUMAN

GO terms

Show/Hide Table
GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0001650 fibrillar center
GO:0001934 positive regulation of protein phosphorylation
GO:0005737 cytoplasm
GO:0005765 lysosomal membrane
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005905 clathrin-coated pit
GO:0005925 focal adhesion
GO:0006898 receptor-mediated endocytosis
GO:0006915 apoptotic process
GO:0007275 multicellular organism development
GO:0008022 protein C-terminus binding
GO:0010718 positive regulation of epithelial to mesenchymal transition
GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0015031 protein transport
GO:0016055 Wnt signaling pathway
GO:0030136 clathrin-coated vesicle
GO:0030335 positive regulation of cell migration
GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway
GO:0030665 clathrin-coated vesicle membrane
GO:0032091 negative regulation of protein binding
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0035026 leading edge cell differentiation
GO:0035615 clathrin adaptor activity
GO:0038024 cargo receptor activity
GO:0043066 negative regulation of apoptotic process
GO:0043231 intracellular membrane-bounded organelle
GO:0045807 positive regulation of endocytosis
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046332 SMAD binding
GO:0060391 positive regulation of SMAD protein signal transduction
GO:0060766 negative regulation of androgen receptor signaling pathway
GO:0061024 membrane organization
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:1903077 negative regulation of protein localization to plasma membrane
GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway
GO:2000370 positive regulation of clathrin-dependent endocytosis
GO:2000643 positive regulation of early endosome to late endosome transport

Diseases

Show/Hide Table

Interactions

12 interactions

InteractorPartnerSourcesPublicationsLink
DAB2Fcho2BioGRID, UniProt20448150 details
DAB2Ppp1cbBioGRID, IntAct26496610 details
DAB2Myh10BioGRID, IntAct26496610 details
DAB2ActbBioGRID, IntAct26496610 details
DAB2FlnbBioGRID, IntAct26496610 details
DAB2Lima1BioGRID, IntAct26496610 details
DAB2Calml3BioGRID, IntAct26496610 details
DAB2Tmod3BioGRID, IntAct26496610 details
DAB2Tpm1BioGRID, IntAct26496610 details
DAB2Myh9BioGRID, IntAct26496610 details
DAB2Myo1cBioGRID, IntAct26496610 details
DAB2Xpo1IntAct26673895 details