Entity Details

Primary name DCTN1
Entity type gene
Source Source Link

Details

PrimaryID1639
RefseqGeneNG_008735
SymbolDCTN1
Namedynactin subunit 1
Chromosome2
Location2p13.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1996-06-19
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsDCTN1_HUMAN

GO terms

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GOName
GO:0000086 G2/M transition of mitotic cell cycle
GO:0000132 establishment of mitotic spindle orientation
GO:0000278 mitotic cell cycle
GO:0000776 kinetochore
GO:0000922 spindle pole
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005814 centriole
GO:0005819 spindle
GO:0005829 cytosol
GO:0005874 microtubule
GO:0005875 microtubule associated complex
GO:0005938 cell cortex
GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport
GO:0007097 nuclear migration
GO:0007399 nervous system development
GO:0007528 neuromuscular junction development
GO:0008017 microtubule binding
GO:0010389 regulation of G2/M transition of mitotic cell cycle
GO:0010457 centriole-centriole cohesion
GO:0015630 microtubule cytoskeleton
GO:0015631 tubulin binding
GO:0016020 membrane
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0019901 protein kinase binding
GO:0021517 ventral spinal cord development
GO:0030286 dynein complex
GO:0030424 axon
GO:0031116 positive regulation of microtubule polymerization
GO:0031122 cytoplasmic microtubule organization
GO:0034454 microtubule anchoring at centrosome
GO:0035371 microtubule plus-end
GO:0036498 IRE1-mediated unfolded protein response
GO:0042147 retrograde transport, endosome to Golgi
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0045171 intercellular bridge
GO:0048156 tau protein binding
GO:0050905 neuromuscular process
GO:0051010 microtubule plus-end binding
GO:0051081 nuclear membrane disassembly
GO:0051301 cell division
GO:0060236 regulation of mitotic spindle organization
GO:0061744 motor behavior
GO:0070050 neuron cellular homeostasis
GO:0072686 mitotic spindle
GO:0090063 positive regulation of microtubule nucleation
GO:0097711 ciliary basal body-plasma membrane docking
GO:0099558 maintenance of synapse structure
GO:0099738 cell cortex region
GO:0120103 centriolar subdistal appendage
GO:1904398 positive regulation of neuromuscular junction development
GO:1905515 non-motile cilium assembly
GO:1990535 neuron projection maintenance

Diseases

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Interactions

20 interactions

InteractorPartnerSourcesPublicationsLink
DCTN1Bicdl1BioGRID, MINT20360680 details
DCTN1Bicd2BioGRID, MINT20360680 22956769 details
DCTN1Kif3aMINT23386061 details
DCTN1Bicdl2BioGRID20360680 details
DCTN1Actr1aBioGRID, IntAct20360068 details
DCTN1Dctn2BioGRID, IntAct20360068 26496610 details
DCTN1Dctn3BioGRID, IntAct20360068 26496610 details
DCTN1Dctn1BioGRID, IntAct20360068 26496610 details
DCTN1Cep76BioGRID, IntAct20360068 details
DCTN1Dync1li1BioGRID, IntAct26496610 details
DCTN1Kctd5BioGRID, IntAct26496610 details
DCTN1Dynlrb1BioGRID, IntAct26496610 details
DCTN1Coro1cBioGRID, IntAct26496610 details
DCTN1Actr1bBioGRID, IntAct26496610 details
DCTN1Dctn4BioGRID, IntAct26496610 details
DCTN1Dctn5BioGRID, IntAct26496610 details
DCTN1Myo1cBioGRID, IntAct26496610 details
DCTN1Prdm16MINT30462309 details
DCTN1MecomMINT30462309 details
DCTN1CenpeBioGRID26496610 details