Entity Details

Primary name DHCR24
Entity type gene
Source Source Link

Details

PrimaryID1718
RefseqGeneNG_008839
SymbolDHCR24
Name24-dehydrocholesterol reductase
Chromosome1
Location1p32.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-04-27
ModificationDate2021-06-13

Ontological Relatives

UniProt IDsDHC24_HUMAN

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0000246 delta24(24-1) sterol reductase activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0006695 cholesterol biosynthetic process
GO:0006915 apoptotic process
GO:0006979 response to oxidative stress
GO:0008202 steroid metabolic process
GO:0009888 tissue development
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
GO:0019899 enzyme binding
GO:0033489 cholesterol biosynthetic process via desmosterol
GO:0033490 cholesterol biosynthetic process via lathosterol
GO:0042605 peptide antigen binding
GO:0043066 negative regulation of apoptotic process
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043588 skin development
GO:0050614 delta24-sterol reductase activity
GO:0071949 FAD binding
GO:1901214 regulation of neuron death

Diseases

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Interactions

6 interactions

InteractorPartnerSourcesPublicationsLink
DHCR24Nedd1BioGRID, IntAct26496610 details
DHCR24FblBioGRID, IntAct26496610 details
DHCR24Atp2a2BioGRID, IntAct26496610 details
DHCR24Ufl1BioGRID, IntAct26496610 details
DHCR24JupBioGRID, IntAct26496610 details
DHCR24MecomMINT30462309 details