Entity Details

Primary name DNMT1
Entity type gene
Source Source Link

Details

PrimaryID1786
RefseqGeneNG_028016
SymbolDNMT1
NameDNA methyltransferase 1
Chromosome19
Location19p13.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-05-07
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsDNMT1_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0003677 DNA binding
GO:0003886 DNA (cytosine-5-)-methyltransferase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006306 DNA methylation
GO:0006325 chromatin organization
GO:0007265 Ras protein signal transduction
GO:0008270 zinc ion binding
GO:0009008 DNA-methyltransferase activity
GO:0010216 maintenance of DNA methylation
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0045814 negative regulation of gene expression, epigenetic
GO:0051571 positive regulation of histone H3-K4 methylation
GO:0051573 negative regulation of histone H3-K9 methylation
GO:0090309 positive regulation of DNA methylation-dependent heterochromatin assembly
GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation
GO:1905460 negative regulation of vascular associated smooth muscle cell apoptotic process
GO:1905931 negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching
GO:1990841 promoter-specific chromatin binding

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
DNMT1MecomMINT30462309 details
DNMT1PcnaBioGRID26496610 details
DNMT1Dctn3BioGRID26496610 details