Entity Details

Primary name DTX1
Entity type gene
Source Source Link

Details

PrimaryID1840
RefseqGene
SymbolDTX1
Namedeltex E3 ubiquitin ligase 1
Chromosome12
Location12q24.13
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-05-15
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsDTX1_HUMAN

GO terms

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GOName
GO:0003713 transcription coactivator activity
GO:0005112 Notch binding
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006351 transcription, DNA-templated
GO:0006366 transcription by RNA polymerase II
GO:0007166 cell surface receptor signaling pathway
GO:0007219 Notch signaling pathway
GO:0008270 zinc ion binding
GO:0008593 regulation of Notch signaling pathway
GO:0010001 glial cell differentiation
GO:0016567 protein ubiquitination
GO:0016604 nuclear body
GO:0017124 SH3 domain binding
GO:0031625 ubiquitin protein ligase binding
GO:0045581 negative regulation of T cell differentiation
GO:0045665 negative regulation of neuron differentiation
GO:0061630 ubiquitin protein ligase activity
GO:1990830 cellular response to leukemia inhibitory factor

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
DTX1Lamp1MINT17028573 details
DTX1Eif3fDIP21124883 details