Entity Details

Primary name E2F1
Entity type gene
Source Source Link

Details

PrimaryID1869
RefseqGeneNG_046988
SymbolE2F1
NameE2F transcription factor 1
Chromosome20
Location20q11.22
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-14
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsE2F1_HUMAN

GO terms

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GOName
GO:0000077 DNA damage checkpoint signaling
GO:0000082 G1/S transition of mitotic cell cycle
GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000987 cis-regulatory region sequence-specific DNA binding
GO:0001216 DNA-binding transcription activator activity
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005739 mitochondrion
GO:0005813 centrosome
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0007283 spermatogenesis
GO:0008134 transcription factor binding
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage
GO:0010628 positive regulation of gene expression
GO:0016032 viral process
GO:0019901 protein kinase binding
GO:0030851 granulocyte differentiation
GO:0030900 forebrain development
GO:0032991 protein-containing complex
GO:0035189 Rb-E2F complex
GO:0043065 positive regulation of apoptotic process
GO:0043276 anoikis
GO:0043392 negative regulation of DNA binding
GO:0043565 sequence-specific DNA binding
GO:0045599 negative regulation of fat cell differentiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046983 protein dimerization activity
GO:0048146 positive regulation of fibroblast proliferation
GO:0048255 mRNA stabilization
GO:0060252 positive regulation of glial cell proliferation
GO:0070317 negative regulation of G0 to G1 transition
GO:0070345 negative regulation of fat cell proliferation
GO:0071398 cellular response to fatty acid
GO:0071456 cellular response to hypoxia
GO:0071466 cellular response to xenobiotic stimulus
GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle
GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator
GO:0090575 RNA polymerase II transcription regulator complex
GO:1900740 positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
GO:1990086 lens fiber cell apoptotic process
GO:1990090 cellular response to nerve growth factor stimulus
GO:1990837 sequence-specific double-stranded DNA binding
GO:2000045 regulation of G1/S transition of mitotic cell cycle

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
E2F1Sp1BioGRID, IntAct8657141 details
E2F1Sirt1UniProt16892051 details
E2F1Nfkb1BioGRID9368006 details