Entity Details

Primary name ABCA1
Entity type gene
Source Source Link

Details

PrimaryID19
RefseqGeneNG_007981
SymbolABCA1
NameATP binding cassette subfamily A member 1
Chromosome9
Location9q31.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-11-30
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsABCA1_HUMAN

GO terms

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GOName
GO:0005102 signaling receptor binding
GO:0005319 lipid transporter activity
GO:0005524 ATP binding
GO:0005548 phospholipid transporter activity
GO:0005768 endosome
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006869 lipid transport
GO:0007040 lysosome organization
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0008203 cholesterol metabolic process
GO:0008320 protein transmembrane transporter activity
GO:0009306 protein secretion
GO:0010745 negative regulation of macrophage derived foam cell differentiation
GO:0010875 positive regulation of cholesterol efflux
GO:0010887 negative regulation of cholesterol storage
GO:0015485 cholesterol binding
GO:0016197 endosomal transport
GO:0019222 regulation of metabolic process
GO:0019905 syntaxin binding
GO:0023061 signal release
GO:0030139 endocytic vesicle
GO:0030522 intracellular receptor signaling pathway
GO:0031210 phosphatidylcholine binding
GO:0031267 small GTPase binding
GO:0032367 intracellular cholesterol transport
GO:0032489 regulation of Cdc42 protein signal transduction
GO:0033344 cholesterol efflux
GO:0033700 phospholipid efflux
GO:0034185 apolipoprotein binding
GO:0034186 apolipoprotein A-I binding
GO:0034188 apolipoprotein A-I receptor activity
GO:0034380 high-density lipoprotein particle assembly
GO:0034616 response to laminar fluid shear stress
GO:0042626 ATPase-coupled transmembrane transporter activity
GO:0042632 cholesterol homeostasis
GO:0043231 intracellular membrane-bounded organelle
GO:0043691 reverse cholesterol transport
GO:0045121 membrane raft
GO:0045332 phospholipid translocation
GO:0045335 phagocytic vesicle
GO:0046623 sphingolipid floppase activity
GO:0048471 perinuclear region of cytoplasm
GO:0051117 ATPase binding
GO:0055091 phospholipid homeostasis
GO:0060155 platelet dense granule organization
GO:0071404 cellular response to low-density lipoprotein particle stimulus
GO:0071806 protein transmembrane transport
GO:0090107 regulation of high-density lipoprotein particle assembly
GO:0090108 positive regulation of high-density lipoprotein particle assembly
GO:0090554 phosphatidylcholine floppase activity
GO:0090556 phosphatidylserine floppase activity
GO:0097708 intracellular vesicle
GO:0120020 cholesterol transfer activity
GO:0140115 export across plasma membrane
GO:0140328 floppase activity

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
ABCA1Lin7cIntAct16192269 details
ABCA1MecomMINT30462309 details